eF-site ID 1tyr-A PDB Code 1tyr Chain A click to enlarge Title TRANSTHYRETIN COMPLEX WITH RETINOIC ACID Classification RETINOL-BINDING Compound TRANSTHYRETIN Source ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; Sequence A:  GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDT WEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWK ALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTA VVTNPKE Description (1)  TRANSTHYRETIN, RETINOIC ACID Functional site 1) chain A residue 15 type sequence K description source : A1 2) chain A residue 16 type sequence V description source : A1 3) chain A residue 17 type sequence L description source : A1 4) chain A residue 106 type sequence T description source : A1 5) chain A residue 107 type sequence I description source : A1 6) chain A residue 108 type sequence A description source : A1 7) chain A residue 109 type sequence A description source : A1 8) chain A residue 110 type sequence L description source : A1 9) chain A residue 117 type sequence S description source : A1 10) chain A residue 118 type sequence T description source : A1 11) chain A residue 119 type sequence T description source : A1 12) chain A residue 120 type sequence A description source : A1 13) chain A residue 121 type sequence V description source : A1 14) chain A residue 15 type sequence K description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 15) chain A residue 17 type sequence L description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 16) chain A residue 17 type sequence L description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 17) chain A residue 106 type sequence T description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 18) chain A residue 108 type sequence A description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 19) chain A residue 108 type sequence A description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 20) chain A residue 109 type sequence A description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 21) chain A residue 110 type sequence L description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 22) chain A residue 110 type sequence L description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 23) chain A residue 117 type sequence S description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 24) chain A residue 117 type sequence S description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 25) chain A residue 119 type sequence T description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 26) chain A residue 121 type sequence V description BINDING SITE FOR RESIDUE 9CR A 131 source : AC2 27) chain A residue 10 type MOD_RES sequence C description Sulfocysteine => ECO:0000269|PubMed:17175208, ECO:0007744|PDB:2H4E source Swiss-Prot : SWS_FT_FI2 28) chain A residue 42 type MOD_RES sequence E description 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012 source Swiss-Prot : SWS_FT_FI3 29) chain A residue 52 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P02767 source Swiss-Prot : SWS_FT_FI4 30) chain A residue 15-30 type prosite sequence KVLDAVRGSPAINVAV description TRANSTHYRETIN_1 Transthyretin signature 1. KVLDavrGsPAinVaV source prosite : PS00768 31) chain A residue 105-117 type prosite sequence YTIAALLSPYSYS description TRANSTHYRETIN_2 Transthyretin signature 2. YTIAalLSPYSYS source prosite : PS00769 32) chain A residue 98 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19167329 source Swiss-Prot : SWS_FT_FI5 33) chain A residue 15 type BINDING sequence K description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 34) chain A residue 117 type BINDING sequence S description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 35) chain A residue 54 type BINDING sequence E description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1

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