|
|
eF-site ID
|
1tym-B |
|
PDB Code
|
1tym |
|
Chain
|
B |
|
click to enlarge
|
|
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Title
|
THE STRUCTURE OF A COMPLEX OF HEXAMERIC INSULIN AND 4'-HYDROXYACETANILIDE |
|
Classification
|
HORMONE |
|
Compound
|
INSULIN |
|
Source
|
Homo sapiens (Human) (INS_HUMAN) |
|
|
Sequence
|
B: |
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
|
|
|
Description
|
(1) |
INSULIN (T3R3) (PH 5.6, 1.0 M NACL) COMPLEXED WITH TWO ZINC IONS AND TYLENOL (4'-HYDROXYACETANILIDE)
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
13 |
| type |
|
| sequence |
E
|
| description |
TYLENOL BINDING SITE, THE TYLENOL MOLECULE IS BOUND IN AN ELLIPTICAL CAVITY BETWEEN R STATE MONOMERS
|
| source |
: TYL
|
|
|
2)
|
chain |
B |
| residue |
17 |
| type |
|
| sequence |
L
|
| description |
TYLENOL BINDING SITE, THE TYLENOL MOLECULE IS BOUND IN AN ELLIPTICAL CAVITY BETWEEN R STATE MONOMERS
|
| source |
: TYL
|
|
|
3)
|
chain |
B |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN B 31
|
| source |
: AC1
|
|
|
4)
|
chain |
B |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN B 31
|
| source |
: AC1
|
|
|
5)
|
chain |
B |
| residue |
10 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE ZN B 31
|
| source |
: AC1
|
|
|
6)
|
chain |
B |
| residue |
13 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE TYL C 100
|
| source |
: AC4
|
|
|
7)
|
chain |
B |
| residue |
17 |
| type |
|
| sequence |
L
|
| description |
BINDING SITE FOR RESIDUE TYL C 100
|
| source |
: AC4
|
|
|
|