|
|
eF-site ID
|
1tyl-C |
|
PDB Code
|
1tyl |
|
Chain
|
C |
|
click to enlarge
|
|
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Title
|
THE STRUCTURE OF A COMPLEX OF HEXAMERIC INSULIN AND 4'-HYDROXYACETANILIDE |
|
Classification
|
HORMONE |
|
Compound
|
INSULIN |
|
Source
|
Homo sapiens (Human) (INS_HUMAN) |
|
|
Sequence
|
C: |
GIVEQCCTSICSLYQLENYCN
|
|
|
Description
|
(1) |
INSULIN (T3R3) (PH 6.4, 0.75 M NACL) COMPLEXED WITH TWO ZINC IONS AND TYLENOL (4'-HYDROXYACETANILIDE)
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
6 |
| type |
|
| sequence |
C
|
| description |
TYLENOL BINDING SITE, THE TYLENOL MOLECULE IS BOUND IN AN ELLIPTICAL CAVITY BETWEEN R STATE MONOMERS
|
| source |
: TYL
|
|
|
2)
|
chain |
C |
| residue |
10 |
| type |
|
| sequence |
I
|
| description |
TYLENOL BINDING SITE, THE TYLENOL MOLECULE IS BOUND IN AN ELLIPTICAL CAVITY BETWEEN R STATE MONOMERS
|
| source |
: TYL
|
|
|
3)
|
chain |
C |
| residue |
11 |
| type |
|
| sequence |
C
|
| description |
TYLENOL BINDING SITE, THE TYLENOL MOLECULE IS BOUND IN AN ELLIPTICAL CAVITY BETWEEN R STATE MONOMERS
|
| source |
: TYL
|
|
|
4)
|
chain |
C |
| residue |
6 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE TYL C 100
|
| source |
: AC4
|
|
|
5)
|
chain |
C |
| residue |
9 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE TYL C 100
|
| source |
: AC4
|
|
|
6)
|
chain |
C |
| residue |
10 |
| type |
|
| sequence |
I
|
| description |
BINDING SITE FOR RESIDUE TYL C 100
|
| source |
: AC4
|
|
|
7)
|
chain |
C |
| residue |
11 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE TYL C 100
|
| source |
: AC4
|
|
|
|