eF-site ID 1tyl-D PDB Code 1tyl Chain D click to enlarge Title THE STRUCTURE OF A COMPLEX OF HEXAMERIC INSULIN AND 4'-HYDROXYACETANILIDE Classification HORMONE Compound INSULIN Source null (INS_HUMAN) Sequence D:  NQHLCGSHLVEALYLVCGERGFFYTPKT Description (1)  INSULIN (T3R3) (PH 6.4, 0.75 M NACL) COMPLEXED WITH TWO ZINC IONS AND TYLENOL (4'-HYDROXYACETANILIDE) Functional site 1) chain D residue 5 type sequence H description TYLENOL BINDING SITE, THE TYLENOL MOLECULE IS BOUND IN AN ELLIPTICAL CAVITY BETWEEN R STATE MONOMERS source : TYL 2) chain D residue 10 type sequence H description TYLENOL BINDING SITE, THE TYLENOL MOLECULE IS BOUND IN AN ELLIPTICAL CAVITY BETWEEN R STATE MONOMERS source : TYL 3) chain D residue 11 type sequence L description TYLENOL BINDING SITE, THE TYLENOL MOLECULE IS BOUND IN AN ELLIPTICAL CAVITY BETWEEN R STATE MONOMERS source : TYL 4) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 31 source : AC2 5) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 31 source : AC2 6) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 31 source : AC2 7) chain D residue 5 type sequence H description BINDING SITE FOR RESIDUE TYL C 100 source : AC4 8) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE TYL C 100 source : AC4 9) chain D residue 11 type sequence L description BINDING SITE FOR RESIDUE TYL C 100 source : AC4 10) chain D residue 14 type sequence A description BINDING SITE FOR RESIDUE TYL C 100 source : AC4

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