eF-site ID 1tx4-B PDB Code 1tx4 Chain B click to enlarge Title RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX Classification COMPLEX(GTPASE ACTIVATN/PROTO-ONCOGENE) Compound P50-RHOGAP Source Homo sapiens (Human) (RHOA_HUMAN) Sequence B:  AIRKKLVIVGDGACGKTCLLIVNSKDQFYVPTVFENYVAD IEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFS IDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDE HTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKD GVREVFEMATRAAL Description Functional site 1) chain B residue 19 type sequence T description BINDING SITE FOR RESIDUE MG B 681 source : AC1 2) chain B residue 37 type sequence T description BINDING SITE FOR RESIDUE MG B 681 source : AC1 3) chain B residue 14 type sequence G description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 4) chain B residue 15 type sequence A description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 5) chain B residue 18 type sequence K description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 6) chain B residue 36 type sequence P description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 7) chain B residue 37 type sequence T description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 8) chain B residue 60 type sequence T description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 9) chain B residue 61 type sequence A description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 10) chain B residue 62 type sequence G description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 11) chain B residue 63 type sequence Q description BINDING SITE FOR RESIDUE ALF B 682 source : AC2 12) chain B residue 15 type sequence A description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 13) chain B residue 16 type sequence C description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 14) chain B residue 17 type sequence G description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 15) chain B residue 18 type sequence K description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 16) chain B residue 19 type sequence T description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 17) chain B residue 20 type sequence C description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 18) chain B residue 30 type sequence F description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 19) chain B residue 34 type sequence Y description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 20) chain B residue 118 type sequence K description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 21) chain B residue 120 type sequence D description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 22) chain B residue 121 type sequence L description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 23) chain B residue 160 type sequence S description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 24) chain B residue 161 type sequence A description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 25) chain B residue 162 type sequence K description BINDING SITE FOR RESIDUE GDP B 680 source : AC3 26) chain B residue 12 type BINDING sequence G description BINDING => ECO:0000269|PubMed:10748207, ECO:0000269|PubMed:12777804 source Swiss-Prot : SWS_FT_FI1 27) chain B residue 117 type BINDING sequence N description BINDING => ECO:0000269|PubMed:10748207, ECO:0000269|PubMed:12777804 source Swiss-Prot : SWS_FT_FI1 28) chain B residue 30 type BINDING sequence F description BINDING => ECO:0000250|UniProtKB:P62820 source Swiss-Prot : SWS_FT_FI2 29) chain B residue 59 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:P62820 source Swiss-Prot : SWS_FT_FI2 30) chain B residue 160 type BINDING sequence S description BINDING => ECO:0000250|UniProtKB:P62820 source Swiss-Prot : SWS_FT_FI2 31) chain B residue 41 type MOD_RES sequence N description (Microbial infection) ADP-ribosylasparagine; by botulinum toxin => ECO:0000305|PubMed:1328215 source Swiss-Prot : SWS_FT_FI5 32) chain B residue 135 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23871831 source Swiss-Prot : SWS_FT_FI9 33) chain B residue 37 type CARBOHYD sequence T description (Microbial infection) O-linked (Glc) threonine; by C.difficile toxins TcdA and TcdB; alternate => ECO:0000269|PubMed:24905543, ECO:0000269|PubMed:7775453, ECO:0000269|PubMed:7777059 source Swiss-Prot : SWS_FT_FI8 34) chain B residue 34 type MOD_RES sequence Y description (Microbial infection) O-AMP-tyrosine; by Haemophilus IbpA; alternate => ECO:0000269|PubMed:19362538 source Swiss-Prot : SWS_FT_FI3 35) chain B residue 37 type MOD_RES sequence T description (Microbial infection) O-AMP-threonine; by Vibrio VopS => ECO:0000269|PubMed:19039103 source Swiss-Prot : SWS_FT_FI4 36) chain B residue 63 type MOD_RES sequence Q description 5-glutamyl serotonin => ECO:0000250|UniProtKB:Q9QUI0 source Swiss-Prot : SWS_FT_FI6 37) chain B residue 34 type CARBOHYD sequence Y description (Microbial infection) O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230; alternate => ECO:0000269|PubMed:24141704 source Swiss-Prot : SWS_FT_FI7

Display surface Download Links