eF-site ID 1twf-B PDB Code 1twf Chain B click to enlarge Title RNA polymerase II complexed with UTP at 2.3 A resolution Classification TRANSCRIPTION Compound DNA-directed RNA polymerase II largest subunit Source ORGANISM_COMMON: baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae; Sequence B:  FEDESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDY TLQDIICEDSTLIEISFGKIYVTKPMVNESDGVTHALYPQ EARLRNLTYSSGLFVDVKKRTYEKVFIGRLPIMLRSKNCY LSEATESDLYKLKECPFDMGGYFIINGSEKVLIAQERSAG NIVQVFKKAAPSPISHVAEIRSALEKGSRFISTLQVKLYG REGSSARTIKATLPYIKQDIPIVIIFRALGIIPDGEILEH ICYDVNDWQMLEMLKPCVEDGFVIQDRETALDFIGRRGTA LGIKKEKRIQYAKDILQKEFLPHITQLEGFESRKAFFLGY MINRLLLCALDRKDQDDRDHFGKKRLDLAGPLLAQLFKTL FKKLTKDIFRYMQRTVELAINAKTITSGLKYALATGNWGA GVSQVLNRYTYSSTLSHLRRTNTPIAKPRQLHNTHWGLVC PAETPEGQACGLVKNLSLMSCISVGTDPMPIITFLSEWGM EPLEDYVPHQSPDATRVFVNGVWHGVHRNPARLMETLRTL RRKGDINPEVSMIRDIREKELKIFTDAGRVYRPLFIVEDD ESLGHKELKVRKGHIAKLMATEYQDEYTWSSLLNEGLVEY IDAEEEESILIAMQPEDLEPDVDPAKRIRVSHHATTFTHC EIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVF LTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQ NAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMD QEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAP GVRVSGEDVIIGKTTPISSKRDASTPLRSTENGIVDQVLV TTNQDGLKFVKVRVRTTKIPQIGDKFASRHGQKGTIGITY RREDMPFTAEGIVPDLIINPHAIPSRMTVAHLIECLLSKV AALSGNEGDASPFTDITVEGISKLLREHGYQSRGFEVMYN GHTGKKLMAQIFFGPTYYQRLRHMVDDKIHARARGPGLRF GEMERDCMIAHGAASFLKERLMEASDAFRVHICGICGLMT VIAKLNHNQFECKGCDNKIDIYQIHIPYAAKLLFQELMAM NITPRLYTDRSRDF Description Functional site 1) chain B residue 1163 type sequence C description BINDING SITE FOR RESIDUE ZN B 3007 source : AC7 2) chain B residue 1166 type sequence C description BINDING SITE FOR RESIDUE ZN B 3007 source : AC7 3) chain B residue 1182 type sequence C description BINDING SITE FOR RESIDUE ZN B 3007 source : AC7 4) chain B residue 1185 type sequence C description BINDING SITE FOR RESIDUE ZN B 3007 source : AC7 5) chain B residue 837 type sequence D description BINDING SITE FOR RESIDUE MN A 3010 source : BC1 6) chain B residue 766 type sequence R description BINDING SITE FOR RESIDUE UTP B 3571 source : BC2 7) chain B residue 986 type sequence Q description BINDING SITE FOR RESIDUE UTP B 3571 source : BC2 8) chain B residue 987 type sequence K description BINDING SITE FOR RESIDUE UTP B 3571 source : BC2 9) chain B residue 1020 type sequence R description BINDING SITE FOR RESIDUE UTP B 3571 source : BC2 10) chain B residue 837 type catalytic sequence D description 788 source MCSA : MCSA1 11) chain B residue 1185 type BINDING sequence C description source Swiss-Prot : SWS_FT_FI2 12) chain B residue 977-989 type prosite sequence GDKFASRHGQKGT description RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT source prosite : PS01166

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