eF-site ID 1ttl_12-A
PDB Code 1ttl
Model 12
Chain A

click to enlarge
Title Omega-conotoxin GVIA, a N-type calcium channel blocker
Classification TOXIN
Compound Omega-conotoxin GVIA
Source ORGANISM_COMMON: geography cone; ORGANISM_SCIENTIFIC: Conus geographus;
Sequence A:  CKSXGSSCSXTSYNCCRSCNXYTKRCYX
Description (1)  Omega-conotoxin GVIA


Functional site

1) chain A
residue 3
type
sequence S
description BINDING SITE FOR RESIDUE NH2 A 28
source : AC1

2) chain A
residue 27
type
sequence Y
description BINDING SITE FOR RESIDUE NH2 A 28
source : AC1

3) chain A
residue 1-26
type prosite
sequence CKSXGSSCSXTSYNCCRSCNXYTKRC
description OMEGA_CONOTOXIN Omega-conotoxin family signature. CKspGsSCSpt...SYnCCR..SCnpyTKRC
source prosite : PS60004

4) chain A
residue 4
type MOD_RES
sequence X
description 4-hydroxyproline => ECO:0000269|PubMed:6509012
source Swiss-Prot : SWS_FT_FI1

5) chain A
residue 10
type MOD_RES
sequence X
description 4-hydroxyproline => ECO:0000269|PubMed:6509012
source Swiss-Prot : SWS_FT_FI1

6) chain A
residue 21
type MOD_RES
sequence X
description 4-hydroxyproline => ECO:0000269|PubMed:6509012
source Swiss-Prot : SWS_FT_FI1

7) chain A
residue 27
type MOD_RES
sequence Y
description Tyrosine amide; in form omega-conotoxin GVIA => ECO:0000269|PubMed:6509012
source Swiss-Prot : SWS_FT_FI2


Display surface

Download
Links