eF-site ID 1tti-A PDB Code 1tti Chain A click to enlarge Title THREE NEW CRYSTAL STRUCTURES OF POINT MUTATION VARIANTS OF MONOTIM: CONFORMATIONAL FLEXIBILITY OF LOOP-1,LOOP-4 AND LOOP-8 Classification ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE) Compound TRIOSEPHOSPHATE ISOMERASE Source (TPIS_TRYBB) Sequence A:  SKPQPIAAANWKSLSELIDLFNSTSINHDVQCVVASTFVH LAMTKERLSHPKFVIAAQNAGNADGLASLKDFGVNWIVLG HSERRWYYGETNEIVADKVAAAVASGFMVIACIGETLQER ESGRTAVVVLTQIAAIAKKLKKADWAKVVIAYEPVWAIGT GKVATPQQAQEAHALIRSWVSSKIGADVAGELRILYGGSV NGKNARTLYQQRDVNGFLVGGASLKPEFVDIIKATQ Description Functional site 1) chain A residue 11 type sequence N description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 2) chain A residue 13 type sequence K description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 3) chain A residue 95 type sequence H description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 4) chain A residue 167 type sequence E description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 5) chain A residue 171 type sequence A description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 6) chain A residue 172 type sequence I description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 7) chain A residue 173 type sequence G description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 8) chain A residue 213 type sequence S description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 9) chain A residue 234 type sequence G description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 10) chain A residue 235 type sequence G description BINDING SITE FOR RESIDUE PGA A 600 source : AC1 11) chain A residue 165-175 type prosite sequence AYEPVWAIGTG description TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG source prosite : PS00171 12) chain A residue 102 type ACT_SITE sequence Y description Electrophile source Swiss-Prot : SWS_FT_FI1 13) chain A residue 174 type ACT_SITE sequence T description Proton acceptor source Swiss-Prot : SWS_FT_FI2 14) chain A residue 11 type BINDING sequence N description source Swiss-Prot : SWS_FT_FI3 15) chain A residue 13 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3

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