eF-site ID 1tte_1-A
PDB Code 1tte
Model 1
Chain A

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Title The Structure of a Class II ubiquitin-conjugating enzyme, Ubc1.
Classification LIGASE
Compound Ubiquitin-conjugating enzyme E2-24 kDa
Source Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (UBC1_YEAST)
Sequence A:  SSRAKRIMKEIQAVKDDPAAHITLEFVSESDIHHLKGTFL
GPPGTPYEGGKFVVDIEVPMEYPFKPPKMQFDTKVYHPNI
SSVTGAICLDILRNAWSPVITLKSALISLQALLQSPEPND
PQDAEVAQHYLRDRESFNKTAALWTRLYASETSNGQKGNV
EESDLYGIDHDLIDEFESQGFEKDKIVEVLRRLGVKSLDP
NDNNTANRIIEELLK
Description


Functional site

1) chain A
residue 88
type ACT_SITE
sequence C
description Glycyl thioester intermediate => ECO:0000255|PROSITE-ProRule:PRU00388
source Swiss-Prot : SWS_FT_FI1

2) chain A
residue 76-92
type prosite
sequence YHPNISSVTGAICLDIL
description UBC_1 Ubiquitin-conjugating (UBC) active site signature. YHPNIssvtGaICLdiL
source prosite : PS00183

3) chain A
residue 93
type CROSSLNK
sequence R
description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
source Swiss-Prot : SWS_FT_FI2


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