|
|
eF-site ID
|
1tsu-ABP |
|
PDB Code
|
1tsu |
|
Chain
|
A, B, P |
|
click to enlarge
|
|
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Title
|
CRYSTAL STRUCTURE OF DECAMER NCP1 SUBSTRATE PEPTIDE IN COMPLEX WITH WILD-TYPE D25N HIV-1 PROTEASE VARIANT |
|
Classification
|
Viral protein/hydrolase |
|
Compound
|
Pol polyprotein |
|
Source
|
null (GAG_HV1H2) |
|
|
Sequence
|
A: |
PQITLWKRPLVTIRIGGQLKEALLNTGADDTVLEEMNLPG
KWKPKMIGGIGGFIKVRQYDQIPVEICGHKAIGTVLVGPT
PVNIIGRNLLTQIGCTLNF
|
| B: |
PQITLWKRPLVTIRIGGQLKEALLNTGADDTVLEEMNLPG
KWKPKMIGGIGGFIKVRQYDQIPVEICGHKAIGTVLVGPT
PVNIIGRNLLTQIGCTLNF
|
| P: |
RQANFLGK
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
P |
| residue |
6 |
| type |
SITE |
| sequence |
F
|
| description |
Cleavage; by viral protease => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
2)
|
chain |
B |
| residue |
78 |
| type |
SITE |
| sequence |
G
|
| description |
Cleavage; by viral protease => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
78 |
| type |
MOD_RES |
| sequence |
G
|
| description |
Phosphotyrosine; by host => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
B |
| residue |
78 |
| type |
MOD_RES |
| sequence |
G
|
| description |
Phosphotyrosine; by host => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|