|
|
eF-site ID
|
1tpd-B |
|
PDB Code
|
1tpd |
|
Chain
|
B |
|
click to enlarge
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Title
|
STRUCTURES OF THE "OPEN" AND "CLOSED" STATE OF TRYPANOSOMAL TRIOSEPHOSPHATE ISOMERASE, AS OBSERVED IN A NEW CRYSTAL FORM: IMPLICATIONS FOR THE REACTION MECHANISM |
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Classification
|
ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE) |
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Compound
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TRIOSEPHOSPHATE ISOMERASE |
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Source
|
(TPIS_TRYBB) |
|
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Sequence
|
B: |
SKPQPIAAANWKCNGSQQSLSELIDLFNSTSINHDVQCVV
ASTFVHLAMTKERLSHPKFVIAAQNAIAKSGAFTGEVSLP
ILKDFGVNWIVLGHSERRAYYGETNEIVADKVAAAVASGF
MVIACIGETLQERESGRTAVVVLTQIAAIAKKLKKADWAK
VVIAYEPVWAIGTGKVATPQQAQEAHALIRSWVSSKIGAD
VAGELRILYGGSVNGKNARTLYQQRDVNGFLVGGASLKPE
FVDIIKATQ
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Description
|
|
Functional site
|
|
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1)
|
chain |
B |
| residue |
95 |
| type |
ACT_SITE |
| sequence |
H
|
| description |
Electrophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
B |
| residue |
167 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
Proton acceptor
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
3)
|
chain |
B |
| residue |
11 |
| type |
BINDING |
| sequence |
N
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
B |
| residue |
13 |
| type |
BINDING |
| sequence |
K
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI3
|
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