eF-site ID 1tkd-B
PDB Code 1tkd
Chain B

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Title T7 DNA polymerase ternary complex with 8 oxo guanosine and dCMP at the elongation site
Classification TRANSFERASE/ELECTRON TRANSPORT/DNA
Compound DNA (5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*(DOC))-3')
Source Enterobacteria phage T7 (Bacteriophage T7) (1TKD)
Sequence B:  KIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPIL
DEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFK
NGEVAATKVGALSKGQLKEFLDANL
Description


Functional site

1) chain B
residue 5
type
sequence I
description BINDING SITE FOR RESIDUE MES A 991
source : AC8

2) chain B
residue 6
type
sequence H
description BINDING SITE FOR RESIDUE MES A 991
source : AC8

3) chain B
residue 11
type
sequence S
description BINDING SITE FOR RESIDUE MES A 991
source : AC8

4) chain B
residue 14
type
sequence T
description BINDING SITE FOR RESIDUE MES A 991
source : AC8

5) chain B
residue 15
type
sequence D
description BINDING SITE FOR RESIDUE MES A 991
source : AC8

6) chain B
residue 24-42
type prosite
sequence LVDFWAEWCGPCKMIAPIL
description THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL
source prosite : PS00194

7) chain B
residue 33
type ACT_SITE
sequence G
description Nucleophile
source Swiss-Prot : SWS_FT_FI1

8) chain B
residue 36
type ACT_SITE
sequence K
description Nucleophile
source Swiss-Prot : SWS_FT_FI1

9) chain B
residue 27
type SITE
sequence F
description Deprotonates C-terminal active site Cys
source Swiss-Prot : SWS_FT_FI2

10) chain B
residue 34
type SITE
sequence P
description Contributes to redox potential value
source Swiss-Prot : SWS_FT_FI3

11) chain B
residue 35
type SITE
sequence C
description Contributes to redox potential value
source Swiss-Prot : SWS_FT_FI3

12) chain B
residue 70
type MOD_RES
sequence Y
description N6-acetyllysine => ECO:0000269|PubMed:18723842
source Swiss-Prot : SWS_FT_FI4


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