|
|
eF-site ID
|
1tim-A |
|
PDB Code
|
1tim |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
STRUCTURE OF TRIOSE PHOSPHATE ISOMERASE FROM CHICKEN MUSCLE |
|
Classification
|
ISOMERASE(INTRAMOLECULAR OXIDOREDUCTASE) |
|
Compound
|
TRIOSEPHOSPHATE ISOMERASE |
|
Source
|
Gallus gallus (Chicken) (TPIS_CHICK) |
|
|
Sequence
|
A: |
APRKFFVGGNWKMNGKRKSLGELIHTLDGAKLSADTEVVC
GAPSIYLDFARQKLDAKIGVAAQNCYKVPKGAFTGEISPA
MIKDIGAAWVILGHSERRHVFGESDELIGQKVAHALAEGL
GVIACIGEKLDEREAGITEKVVFQETKAIADNVKDWSKVV
LAYEPVWAIGTGKTATPQQAQEVHEKLRGWLKTHVSDAVA
VQSRIIYGGSVTGGNCKELASQHDVDGFLVGGASLKPEFV
DIINAKH
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
12 |
| type |
catalytic |
| sequence |
W
|
| description |
324
|
| source |
MCSA : MCSA1
|
|
|
2)
|
chain |
A |
| residue |
14 |
| type |
catalytic |
| sequence |
M
|
| description |
324
|
| source |
MCSA : MCSA1
|
|
|
3)
|
chain |
A |
| residue |
96 |
| type |
catalytic |
| sequence |
S
|
| description |
324
|
| source |
MCSA : MCSA1
|
|
|
4)
|
chain |
A |
| residue |
98 |
| type |
catalytic |
| sequence |
R
|
| description |
324
|
| source |
MCSA : MCSA1
|
|
|
5)
|
chain |
A |
| residue |
166 |
| type |
catalytic |
| sequence |
P
|
| description |
324
|
| source |
MCSA : MCSA1
|
|
|
6)
|
chain |
A |
| residue |
172 |
| type |
catalytic |
| sequence |
T
|
| description |
324
|
| source |
MCSA : MCSA1
|
|
|
7)
|
chain |
A |
| residue |
211 |
| type |
catalytic |
| sequence |
S
|
| description |
324
|
| source |
MCSA : MCSA1
|
|
|
8)
|
chain |
A |
| residue |
163-173 |
| type |
prosite |
| sequence |
AYEPVWAIGTG
|
| description |
TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG
|
| source |
prosite : PS00171
|
|
|
9)
|
chain |
A |
| residue |
96 |
| type |
ACT_SITE |
| sequence |
S
|
| description |
Electrophile => ECO:0000269|PubMed:8130195, ECO:0007744|PDB:1TPH
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
10)
|
chain |
A |
| residue |
166 |
| type |
ACT_SITE |
| sequence |
P
|
| description |
Proton acceptor => ECO:0000269|PubMed:8130195, ECO:0007744|PDB:1TPH
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
11)
|
chain |
A |
| residue |
12 |
| type |
BINDING |
| sequence |
W
|
| description |
BINDING => ECO:0000269|PubMed:8130195, ECO:0007744|PDB:1TPH
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
12)
|
chain |
A |
| residue |
14 |
| type |
BINDING |
| sequence |
M
|
| description |
BINDING => ECO:0000269|PubMed:8130195, ECO:0007744|PDB:1TPH
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|