|
|
eF-site ID
|
1tho-A |
|
PDB Code
|
1tho |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
CRYSTAL STRUCTURE OF A MUTANT ESCHERICHIA COLI THIOREDOXIN WITH AN ARGININE INSERTION IN THE ACTIVE SITE |
|
Classification
|
ELECTRON TRANSPORT |
|
Compound
|
THIOREDOXIN |
|
Source
|
null (THIO_ECOLI) |
|
|
Sequence
|
A: |
SDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGRPCKMIA
PILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLL
LFKNGEVAATKVGALSKGQLKEFLDANLA
|
|
|
Description
|
(1) |
THIOREDOXIN MUTANT WITH ARG INSERTED BETWEEN GLY 33 AND PRO 34 (33R34)
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
1 |
| type |
|
| sequence |
S
|
| description |
BINDING SITE FOR RESIDUE CU A 109
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
2 |
| type |
|
| sequence |
D
|
| description |
BINDING SITE FOR RESIDUE CU A 109
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
69 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000269|PubMed:18723842
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
4)
|
chain |
A |
| residue |
35 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Nucleophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
A |
| residue |
32 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Nucleophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
A |
| residue |
26 |
| type |
SITE |
| sequence |
D
|
| description |
Deprotonates C-terminal active site Cys
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
A |
| residue |
34 |
| type |
SITE |
| sequence |
P
|
| description |
Contributes to redox potential value
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
8)
|
chain |
A |
| residue |
33 |
| type |
SITE |
| sequence |
G
|
| description |
Contributes to redox potential value
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|