eF-site ID 1tgv-A
PDB Code 1tgv
Chain A

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Title Structure of E. coli Uridine Phosphorylase complexed with 5-Fluorouridine and sulfate
Classification TRANSFERASE
Compound uridine phosphorylase
Source null (UDP_ECOLI)
Sequence A:  SDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVK
LASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQ
LGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHF
APLEFPAVADFECTTALVEAAKSIGATTHVGVTASSDTFY
PGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLL
TMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESHAVK
IVVEAARRLL
Description


Functional site

1) chain A
residue 26
type
sequence G
description BINDING SITE FOR RESIDUE SO4 A 482
source : AC1

2) chain A
residue 30
type
sequence R
description BINDING SITE FOR RESIDUE SO4 A 482
source : AC1

3) chain A
residue 91
type
sequence R
description BINDING SITE FOR RESIDUE SO4 A 482
source : AC1

4) chain A
residue 92
type
sequence I
description BINDING SITE FOR RESIDUE SO4 A 482
source : AC1

5) chain A
residue 93
type
sequence G
description BINDING SITE FOR RESIDUE SO4 A 482
source : AC1

6) chain A
residue 94
type
sequence T
description BINDING SITE FOR RESIDUE SO4 A 482
source : AC1

7) chain A
residue 48
type
sequence R
description BINDING SITE FOR RESIDUE SO4 B 682
source : AC2

8) chain A
residue 49
type
sequence E
description BINDING SITE FOR RESIDUE K A 1001
source : AC3

9) chain A
residue 69
type
sequence I
description BINDING SITE FOR RESIDUE K A 1001
source : AC3

10) chain A
residue 73
type
sequence S
description BINDING SITE FOR RESIDUE K A 1001
source : AC3

11) chain A
residue 91
type
sequence R
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

12) chain A
residue 94
type
sequence T
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

13) chain A
residue 95
type
sequence T
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

14) chain A
residue 96
type
sequence G
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

15) chain A
residue 162
type
sequence F
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

16) chain A
residue 166
type
sequence Q
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

17) chain A
residue 168
type
sequence R
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

18) chain A
residue 196
type
sequence E
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

19) chain A
residue 197
type
sequence M
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

20) chain A
residue 198
type
sequence E
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

21) chain A
residue 220
type
sequence I
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

22) chain A
residue 221
type
sequence V
description BINDING SITE FOR RESIDUE 5UD A 3001
source : AC4

23) chain A
residue 8
type
sequence H
description BINDING SITE FOR RESIDUE 5UD B 5002
source : AC5

24) chain A
residue 8
type catalytic
sequence H
description 787
source MCSA : MCSA1

25) chain A
residue 80
type catalytic
sequence E
description 787
source MCSA : MCSA1

26) chain A
residue 168
type catalytic
sequence R
description 787
source MCSA : MCSA1

27) chain A
residue 223
type catalytic
sequence R
description 787
source MCSA : MCSA1

28) chain A
residue 66-81
type prosite
sequence STGIGGPSTSIAVEEL
description PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL
source prosite : PS01232


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