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eF-site ID
|
1tcy-A |
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PDB Code
|
1tcy |
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Chain
|
A |
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click to enlarge
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Title
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DISSECTION OF THE FUNCTIONAL ROLE OF STRUCTURAL ELEMENTS OF TYROSINE-63 IN THE CATALYTIC ACTION OF HUMAN LYSOZYME |
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Classification
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HYDROLASE (O-GLYCOSYL) |
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Compound
|
HUMAN LYSOZYME |
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Source
|
null (LYSC_HUMAN) |
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Sequence
|
A: |
KVFERCELARTLKRLGMDGYRGISLANWMCLAKWESGYNT
RATNYNAGDRSTDYGIFQINSRFWCNDGKTPGAVNACHLS
CSALLQDNIADAVACAKRVVRDPQGIRAWVAWRNRCQNRD
VRQYVQGCGV
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Description
|
(1) |
LYSOZYME (E.C.3.2.1.17) MUTANT WITH TYR 63 REPLACED BY PHE (Y63F)
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Functional site
|
|
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1)
|
chain |
A |
| residue |
77-95 |
| type |
prosite |
| sequence |
CHLSCSALLQDNIADAVAC
|
| description |
GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. ChlsCsaLlqdNIadavaC
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| source |
prosite : PS00128
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2)
|
chain |
A |
| residue |
35 |
| type |
ACT_SITE |
| sequence |
E
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
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3)
|
chain |
A |
| residue |
53 |
| type |
ACT_SITE |
| sequence |
D
|
| description |
|
| source |
Swiss-Prot : SWS_FT_FI1
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