eF-site ID 1tcd-AB PDB Code 1tcd Chain A, B click to enlarge Title TRYPANOSOMA CRUZI TRIOSEPHOSPHATE ISOMERASE Classification ISOMERASE Compound TRIOSEPHOSPHATE ISOMERASE Source Trypanosoma cruzi (TPIS_TRYCR) Sequence A:  KPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVVA PTFLHIPMTKARLTNPKFQIAAQNAITRSGAFTGEVSLQI LKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGFH VIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSRV VIAYEPVWAIGTGKVATPQQAQEVHELLRRWVRSKLGTDI AAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPEF VEIIEATK B:  SKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCVV APTFLHIPMTKARLTNPKFQIAAQNAITRSGAFTGEVSLQ ILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAGF HVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWSR VVIAYEPVWAIGTGKVATPQQAQEVHELLRRWVRSKLGTD IAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKPE FVEIIEATK Description Functional site 1) chain A residue 166-176 type prosite sequence AYEPVWAIGTG description TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG source prosite : PS00171 2) chain A residue 96 type ACT_SITE sequence H description Electrophile => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 3) chain B residue 96 type ACT_SITE sequence H description Electrophile => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 4) chain A residue 168 type ACT_SITE sequence E description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 5) chain B residue 168 type ACT_SITE sequence E description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 6) chain A residue 12 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 7) chain A residue 14 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 8) chain B residue 12 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 9) chain B residue 14 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

Display surface Download Links