eF-site ID 1t3t-A PDB Code 1t3t Chain A click to enlarge Title Structure of Formylglycinamide synthetase Classification LIGASE Compound Phosphoribosylformylglycinamidine synthase Source Salmonella typhimurium (PUR4_SALTY) Sequence A:  GLVPRGSHMMEILRGSPALSAFRINKLLARFQAANLQVHN IYAEYVHFADLNAPLNDSEQAQLTRLLQYGPALSSHTPAG KLLLVTPRPGTISPWSSKATDIAHNCGLQQVDRLERGVAY YIEASTLTAEQWRQVAAELHDRMMETVFSSLTDAEKLFIH HQPAPVSSVDLLGEGRQALIDANLRLGLALAEDEIDYLQE AFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGKP QPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSAVGRYF ADHNTGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGS GGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEED FGKPERIVTALDIMTEGPLGGAAFNNEFGRPALTGYFRTY EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEIVV GAKLIVLGGPAMNIGFASVQRDNPEMERRCQEVIDRCWQL GDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDIL SDEPGMSPLEIWCNESQERYVLAVAADQLPLFDELCKRER APYAVIGDATEEQHLSLHDNHFDNQPIDLPLDVLLGKTPK MTRDVQTLKAKGDALNRADITIADAVKRVLHLPTVAEKTF LVTIGDRTVTGMVARDQMVGPWQVPVADCAVTTASLDSYY GEAMSIGERAPVALLDFAASARLAVGEALTNIAATQIGDI KRIKLSANWMAAAGHPGEDAGLYDAVKAVGEELCPQLGLT IPVGKDSMSMKTRWQEGNEQREMTSPLSLVISAFARVEDV RHTLTPQLSTEDNALLLIDLGKGHNALGATALAQVYRQLG DKPADVRDVAQLKGFYDAMQALVAARKLLAWHDRSDGGLL VTLAEMAFAGHCGVQVDIAALGDDHLAALFNEELGGVIQV RAEDRDAVEALLAQYGLADCVHYLGQALAGDRFVITANDQ TVFSESRTTLRVWWAETTWQMQRLRDNPQCADQEHEAKAN DTDPGLNVKLSFDINEDIAAPYIATGARPKVAVLREQGVN SHVEMAAAFHRAGFDAIDVHMSDLLGGRIGLGNFHALVAC GGFSYGDVLGAGEGWAKSILFNHRVRDEFETFFHRPQTLA LGVXNGCQMMSNLRELIPGSELWPRFVRNHSDRFEARFSL VEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVRDDAHLAA LESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTEN GRVTIMMPHPERVFRTVANSWHPENWGEDSPWMRIFRNAR KQLG Description (1)  Phosphoribosylformylglycinamidine synthase (E.C.6.3.5.3) Functional site 1) chain A residue 679 type sequence D description BINDING SITE FOR RESIDUE MG A 2006 source : AC1 2) chain A residue 722 type sequence N description BINDING SITE FOR RESIDUE MG A 2006 source : AC1 3) chain A residue 884 type sequence D description BINDING SITE FOR RESIDUE MG A 2006 source : AC1 4) chain A residue 718 type sequence E description BINDING SITE FOR RESIDUE MG A 2007 source : AC2 5) chain A residue 216 type sequence H description BINDING SITE FOR RESIDUE SO4 A 2001 source : AC4 6) chain A residue 294 type sequence E description BINDING SITE FOR RESIDUE SO4 A 2001 source : AC4 7) chain A residue 504 type sequence G description BINDING SITE FOR RESIDUE SO4 A 2001 source : AC4 8) chain A residue 505 type sequence A description BINDING SITE FOR RESIDUE SO4 A 2001 source : AC4 9) chain A residue 776 type sequence K description BINDING SITE FOR RESIDUE SO4 A 2001 source : AC4 10) chain A residue 216 type sequence H description BINDING SITE FOR RESIDUE SO4 A 2002 source : AC5 11) chain A residue 295 type sequence T description BINDING SITE FOR RESIDUE SO4 A 2002 source : AC5 12) chain A residue 296 type sequence H description BINDING SITE FOR RESIDUE SO4 A 2002 source : AC5 13) chain A residue 297 type sequence N description BINDING SITE FOR RESIDUE SO4 A 2002 source : AC5 14) chain A residue 298 type sequence H description BINDING SITE FOR RESIDUE SO4 A 2002 source : AC5 15) chain A residue 778 type sequence S description BINDING SITE FOR RESIDUE SO4 A 2002 source : AC5 16) chain A residue 690 type sequence Y description BINDING SITE FOR RESIDUE SO4 A 2009 source : AC6 17) chain A residue 812 type sequence R description BINDING SITE FOR RESIDUE SO4 A 2009 source : AC6 18) chain A residue 1228 type sequence K description BINDING SITE FOR RESIDUE SO4 A 2009 source : AC6 19) chain A residue 1229 type sequence V description BINDING SITE FOR RESIDUE SO4 A 2009 source : AC6 20) chain A residue 1176 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 2010 source : AC7 21) chain A residue 1183 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 2010 source : AC7 22) chain A residue 1184 type sequence G description BINDING SITE FOR RESIDUE SO4 A 2010 source : AC7 23) chain A residue 1185 type sequence M description BINDING SITE FOR RESIDUE SO4 A 2010 source : AC7 24) chain A residue 1186 type sequence V description BINDING SITE FOR RESIDUE SO4 A 2010 source : AC7 25) chain A residue 1040 type sequence P description BINDING SITE FOR RESIDUE SO4 A 2011 source : AC8 26) chain A residue 1041 type sequence K description BINDING SITE FOR RESIDUE SO4 A 2011 source : AC8 27) chain A residue 1086 type sequence H description BINDING SITE FOR RESIDUE SO4 A 2011 source : AC8 28) chain A residue 1086 type sequence H description BINDING SITE FOR RESIDUE SO4 A 2012 source : AC9 29) chain A residue 1126 type sequence R description BINDING SITE FOR RESIDUE SO4 A 2012 source : AC9 30) chain A residue 1127 type sequence P description BINDING SITE FOR RESIDUE SO4 A 2012 source : AC9 31) chain A residue 1128 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 2012 source : AC9 32) chain A residue 1129 type sequence T description BINDING SITE FOR RESIDUE SO4 A 2012 source : AC9 33) chain A residue 386 type sequence T description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 34) chain A residue 387 type sequence G description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 35) chain A residue 388 type sequence Y description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 36) chain A residue 389 type sequence F description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 37) chain A residue 652 type sequence L description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 38) chain A residue 668 type sequence Q description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 39) chain A residue 676 type sequence P description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 40) chain A residue 678 type sequence A description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 41) chain A residue 679 type sequence D description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 42) chain A residue 718 type sequence E description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 43) chain A residue 722 type sequence N description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 44) chain A residue 886 type sequence S description BINDING SITE FOR RESIDUE ADP A 2005 source : BC1 45) chain A residue 1135 type ACT_SITE sequence X description Nucleophile => ECO:0000255|HAMAP-Rule:MF_00419 source Swiss-Prot : SWS_FT_FI1 46) chain A residue 1260 type ACT_SITE sequence H description ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00419 source Swiss-Prot : SWS_FT_FI2 47) chain A residue 1262 type ACT_SITE sequence E description ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00419 source Swiss-Prot : SWS_FT_FI2 48) chain A residue 307 type BINDING sequence G description BINDING => ECO:0000255|HAMAP-Rule:MF_00419 source Swiss-Prot : SWS_FT_FI3 49) chain A residue 386 type BINDING sequence T description source Swiss-Prot : SWS_FT_FI4 50) chain A residue 678 type BINDING sequence A description source Swiss-Prot : SWS_FT_FI4 51) chain A residue 886 type BINDING sequence S description source Swiss-Prot : SWS_FT_FI4 52) chain A residue 679 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_00419, ECO:0000269|PubMed:15301531, ECO:0000269|PubMed:22683785, ECO:0000269|PubMed:24223728 source Swiss-Prot : SWS_FT_FI5 53) chain A residue 718 type BINDING sequence E description BINDING => ECO:0000255|HAMAP-Rule:MF_00419, ECO:0000269|PubMed:15301531, ECO:0000269|PubMed:22683785, ECO:0000269|PubMed:24223728 source Swiss-Prot : SWS_FT_FI5 54) chain A residue 722 type BINDING sequence N description BINDING => ECO:0000255|HAMAP-Rule:MF_00419, ECO:0000269|PubMed:15301531, ECO:0000269|PubMed:22683785, ECO:0000269|PubMed:24223728 source Swiss-Prot : SWS_FT_FI5 55) chain A residue 884 type BINDING sequence D description BINDING => ECO:0000255|HAMAP-Rule:MF_00419, ECO:0000269|PubMed:15301531, ECO:0000269|PubMed:22683785, ECO:0000269|PubMed:24223728 source Swiss-Prot : SWS_FT_FI5

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