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eF-site ID
|
1syq-AB |
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PDB Code
|
1syq |
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Chain
|
A, B |
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click to enlarge
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Title
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Human vinculin head domain VH1, residues 1-258, in complex with human talin's vinculin binding site 1, residues 607-636 |
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Classification
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CELL ADHESION |
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Compound
|
vinculin isoform VCL |
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Source
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null (TLN1_HUMAN) |
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Sequence
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A: |
HMPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPD
LTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFI
KVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGT
SDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVT
YTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVK
ELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSA
EINEIIRVLQLTSWDEDAW
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| B: |
PLLQAAKGLAGAVSELLRSAQPASA
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Description
|
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Functional site
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|
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1)
|
chain |
B |
| residue |
620 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P26039
|
| source |
Swiss-Prot : SWS_FT_FI1
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|
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2)
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chain |
A |
| residue |
173 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
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| source |
Swiss-Prot : SWS_FT_FI2
|
|
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3)
|
chain |
A |
| residue |
162-182 |
| type |
prosite |
| sequence |
KNLGPGMTKMAKMIDERQQEL
|
| description |
VINCULIN_1 Vinculin family talin-binding region signature. KnLgpgMtkMakmideRQQEL
|
| source |
prosite : PS00663
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