eF-site ID 1sux-A PDB Code 1sux Chain A click to enlarge Title CRYSTALLOGRAPHIC ANALYSIS OF THE COMPLEX BETWEEN TRIOSEPHOSPHATE ISOMERASE FROM TRYPANOSOMA CRUZI AND 3-(2-benzothiazolylthio)-1-propanesulfonic acid Classification ISOMERASE Compound Triosephosphate isomerase, glycosomal Source Trypanosoma cruzi (TPIS_TRYCR) Sequence A:  ASKPQPIAAANWKCNGSESLLVPLIETLNAATFDHDVQCV VAPTFLHIPMTKARLTNPKFQIAAQNAITRSGAFTGEVSL QILKDYGISWVVLGHSERRLYYGETNEIVAEKVAQACAAG FHVIVCVGETNEEREAGRTAAVVLTQLAAVAQKLSKEAWS RVVIAYEPVWAIGTGKVATPQQAQEVHELLRRWVRSKLGT DIAAQLRILYGGSVTAKNARTLYQMRDINGFLVGGASLKP EFVEIIEATK Description Functional site 1) chain A residue 193 type sequence R description BINDING SITE FOR RESIDUE SO4 A 501 source : AC1 2) chain A residue 3 type sequence S description BINDING SITE FOR RESIDUE SO4 A 502 source : AC2 3) chain A residue 4 type sequence K description BINDING SITE FOR RESIDUE SO4 A 502 source : AC2 4) chain A residue 227 type sequence R description BINDING SITE FOR RESIDUE SO4 A 502 source : AC2 5) chain A residue 2 type sequence A description BINDING SITE FOR RESIDUE SO4 A 503 source : AC3 6) chain A residue 227 type sequence R description BINDING SITE FOR RESIDUE SO4 A 503 source : AC3 7) chain A residue 14 type sequence K description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 8) chain A residue 172 type sequence A description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 9) chain A residue 173 type sequence I description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 10) chain A residue 174 type sequence G description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 11) chain A residue 213 type sequence G description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 12) chain A residue 214 type sequence S description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 13) chain A residue 235 type sequence G description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 14) chain A residue 236 type sequence G description BINDING SITE FOR RESIDUE SO4 A 504 source : AC4 15) chain A residue 196 type sequence R description BINDING SITE FOR RESIDUE SO4 A 506 source : AC6 16) chain A residue 71 type sequence R description BINDING SITE FOR RESIDUE BTS B 401 source : AC8 17) chain A residue 141 type sequence A description BINDING SITE FOR RESIDUE BTS B 401 source : AC8 18) chain A residue 146 type sequence T description BINDING SITE FOR RESIDUE BTS B 401 source : AC8 19) chain A residue 190 type sequence L description BINDING SITE FOR RESIDUE BTS B 401 source : AC8 20) chain A residue 166-176 type prosite sequence AYEPVWAIGTG description TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG source prosite : PS00171 21) chain A residue 96 type ACT_SITE sequence H description Electrophile => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 22) chain A residue 168 type ACT_SITE sequence E description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 23) chain A residue 12 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3 24) chain A residue 14 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI3

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