eF-site ID 1ssp-E PDB Code 1ssp Chain E click to enlarge Title WILD-TYPE URACIL-DNA GLYCOSYLASE BOUND TO URACIL-CONTAINING DNA Classification HYDROLASE/DNA Compound 5'-D(*CP*TP*GP*TP*(D1P)P*AP*TP*CP*TP*T)-3' Source Homo sapiens (Human) (1SSP) Sequence E:  MEFFGESWKKHLSGEFGKPYFIKLMGFVAEERKHYTVYPP PHQVFTWTQMCDIKDVKVVILGQDPYHGPNQAHGLCFSVQ RPVPPPPSLENIYKELSTDIEDFVHPGHGDLSGWAKQGVL LLNAVLTVRAHQANSHKERGWEQFTDAVVSWLNQNSNGLV FLLWGSYAQKKGSAIDRKRHHVLQTAHPSPLSVYRGFFGC RHFSKTNELLQKSGKKPIDWKEL Description Functional site 1) chain E residue 143 type sequence G description BINDING SITE FOR RESIDUE URA E 55 source : AC1 2) chain E residue 144 type sequence Q description BINDING SITE FOR RESIDUE URA E 55 source : AC1 3) chain E residue 145 type sequence D description BINDING SITE FOR RESIDUE URA E 55 source : AC1 4) chain E residue 147 type sequence Y description BINDING SITE FOR RESIDUE URA E 55 source : AC1 5) chain E residue 157 type sequence C description BINDING SITE FOR RESIDUE URA E 55 source : AC1 6) chain E residue 158 type sequence F description BINDING SITE FOR RESIDUE URA E 55 source : AC1 7) chain E residue 204 type sequence N description BINDING SITE FOR RESIDUE URA E 55 source : AC1 8) chain E residue 268 type sequence H description BINDING SITE FOR RESIDUE URA E 55 source : AC1 9) chain E residue 286 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2 10) chain E residue 145 type ACT_SITE sequence D description Proton acceptor => ECO:0000255|HAMAP-Rule:MF_03166 source Swiss-Prot : SWS_FT_FI1 11) chain E residue 138-147 type prosite sequence KVVILGQDPY description U_DNA_GLYCOSYLASE Uracil-DNA glycosylase signature. KVVIlGQDPY source prosite : PS00130

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