eF-site ID 1srn-A PDB Code 1srn Chain A click to enlarge Title THE REFINED CRYSTAL STRUCTURE OF A FULLY ACTIVE SEMISYNTHETIC RIBONUCLEASE AT 1.8 ANGSTROMS RESOLUTION Classification HYDROLASE (NUCLEIC ACID,RNA) Compound RIBONUCLEASE A Source Bos taurus (Bovine) (RNAS1_BOVIN) Sequence A:  KETAAAKFERQHMDSSTSAASSSNYCNQMMKSRNLTKDRC KPVNTFVHESLADVQAVCSQKNVACKNGQTNCYQSYSTMS ITDCRETGSSKYPNCAYKTTQANKHIIVACEGN Description (1)  SEMISYNTHETIC RIBONUCLEASE A (RNASE 1-118(COLON)111-124) (E.C.3.1.27.5) Functional site 1) chain A residue 11 type sequence Q description BINDING SITE FOR RESIDUE SO4 A 125 source : AC1 2) chain A residue 12 type sequence H description BINDING SITE FOR RESIDUE SO4 A 125 source : AC1 3) chain A residue 41 type sequence K description BINDING SITE FOR RESIDUE SO4 A 125 source : AC1 4) chain A residue 1 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI3 5) chain A residue 7 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI3 6) chain A residue 37 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI3 7) chain A residue 41 type CARBOHYD sequence K description N-linked (Glc) (glycation) lysine; in vitro => ECO:0000269|PubMed:4030761 source Swiss-Prot : SWS_FT_FI3 8) chain A residue 34 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine; partial => ECO:0000269|PubMed:19358553 source Swiss-Prot : SWS_FT_FI4 9) chain A residue 7 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 10) chain A residue 10 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 11) chain A residue 41 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 12) chain A residue 66 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI2 13) chain A residue 85 type BINDING sequence R description source Swiss-Prot : SWS_FT_FI2 14) chain A residue 40-46 type prosite sequence CKPVNTF description RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKpvNTF source prosite : PS00127

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