eF-site ID 1sow-AB PDB Code 1sow Chain A, B click to enlarge Title T. gondii bradyzoite-specific LDH (LDH2) in complex with NAD and oxalate Classification OXIDOREDUCTASE Compound L-lactate dehydrogenase Source Toxoplasma gondii (LDH_TOXGO) Sequence A:  TVSRRKKIAMIGSGMIGGTMGYLCVLRELADVVLFDVVTG MPEGKALDDSQATSIADTNVSVTSANQYEKIAGSDVVIIT AGLTKVPGKSDKEWSRNDLLPFNAKIIREVAQGVKKYCPL AFVIVVTNPLDCMVKCFHEASGLPKNMVCGMANVLDSARF RRFIADQLEISPRDIQATVIGTHGDHMLPLARYVTVNGFP LREFIKKGKMTEAKLAEIVERTKKAGGEIVRLLGQGSAYY APALSAITMAQAFLKDEKRVLPCSVYCQGEYGLHDMFIGL PAVIGGGGIEQVIELELTHEEQECFRKSVDDVVELNKSLA AL B:  GTVSRRKKIAMIGSGMIGGTMGYLCVLRELADVVLFDVVT GMPEGKALDDSQATSIADTNVSVTSANQYEKIAGSDVVII TAGLTKVPGKSDKEWSRNDLLPFNAKIIREVAQGVKKYCP LAFVIVVTNPLDCMVKCFHEASGLPKNMVCGMANVLDSAR FRRFIADQLEISPRDIQATVIGTHGDHMLPLARYVTVNGF PLREFIKKGKMTEAKLAEIVERTKKAGGEIVRLLGQGSAY YAPALSAITMAQAFLKDEKRVLPCSVYCQGEYGLHDMFIG LPAVIGGGGIEQVIELELTHEEQECFRKSVDDVVELNKSL AAL Description Functional site 1) chain A residue 107 type sequence W description BINDING SITE FOR RESIDUE OXL A 402 source : AC1 2) chain A residue 109 type sequence R description BINDING SITE FOR RESIDUE OXL A 402 source : AC1 3) chain A residue 140 type sequence N description BINDING SITE FOR RESIDUE OXL A 402 source : AC1 4) chain A residue 171 type sequence R description BINDING SITE FOR RESIDUE OXL A 402 source : AC1 5) chain A residue 195 type sequence H description BINDING SITE FOR RESIDUE OXL A 402 source : AC1 6) chain A residue 236 type sequence G description BINDING SITE FOR RESIDUE OXL A 402 source : AC1 7) chain B residue 107 type sequence W description BINDING SITE FOR RESIDUE OXL B 502 source : AC2 8) chain B residue 109 type sequence R description BINDING SITE FOR RESIDUE OXL B 502 source : AC2 9) chain B residue 140 type sequence N description BINDING SITE FOR RESIDUE OXL B 502 source : AC2 10) chain B residue 171 type sequence R description BINDING SITE FOR RESIDUE OXL B 502 source : AC2 11) chain B residue 195 type sequence H description BINDING SITE FOR RESIDUE OXL B 502 source : AC2 12) chain B residue 236 type sequence G description BINDING SITE FOR RESIDUE OXL B 502 source : AC2 13) chain B residue 246 type sequence A description BINDING SITE FOR RESIDUE OXL B 502 source : AC2 14) chain A residue 29 type sequence G description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 15) chain A residue 30 type sequence M description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 16) chain A residue 31 type sequence I description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 17) chain A residue 53 type sequence D description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 18) chain A residue 54 type sequence V description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 19) chain A residue 55 type sequence V description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 20) chain A residue 58 type sequence M description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 21) chain A residue 97 type sequence T description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 22) chain A residue 98 type sequence A description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 23) chain A residue 99 type sequence G description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 24) chain A residue 100 type sequence L description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 25) chain A residue 101 type sequence T description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 26) chain A residue 119 type sequence I description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 27) chain A residue 122 type sequence E description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 28) chain A residue 138 type sequence V description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 29) chain A residue 139 type sequence T description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 30) chain A residue 140 type sequence N description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 31) chain A residue 163 type sequence M description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 32) chain A residue 167 type sequence L description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 33) chain A residue 195 type sequence H description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 34) chain A residue 246 type sequence A description BINDING SITE FOR RESIDUE NAD A 401 source : AC3 35) chain B residue 29 type sequence G description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 36) chain B residue 30 type sequence M description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 37) chain B residue 31 type sequence I description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 38) chain B residue 52 type sequence F description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 39) chain B residue 53 type sequence D description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 40) chain B residue 54 type sequence V description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 41) chain B residue 55 type sequence V description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 42) chain B residue 58 type sequence M description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 43) chain B residue 97 type sequence T description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 44) chain B residue 98 type sequence A description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 45) chain B residue 99 type sequence G description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 46) chain B residue 100 type sequence L description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 47) chain B residue 101 type sequence T description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 48) chain B residue 122 type sequence E description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 49) chain B residue 138 type sequence V description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 50) chain B residue 139 type sequence T description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 51) chain B residue 140 type sequence N description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 52) chain B residue 163 type sequence M description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 53) chain B residue 167 type sequence L description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 54) chain B residue 195 type sequence H description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 55) chain B residue 246 type sequence A description BINDING SITE FOR RESIDUE NAD B 501 source : AC4 56) chain A residue 195 type ACT_SITE sequence H description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 57) chain B residue 195 type ACT_SITE sequence H description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 58) chain A residue 53 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 59) chain A residue 109 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 60) chain A residue 140 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 61) chain A residue 171 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 62) chain B residue 53 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 63) chain B residue 109 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 64) chain B residue 140 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 65) chain B residue 171 type BINDING sequence R description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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