|
|
eF-site ID
|
1sks-B |
|
PDB Code
|
1sks |
|
Chain
|
B |
|
click to enlarge
|
|
|
Title
|
Binary 3' complex of T7 DNA polymerase with a DNA primer/template containing a cis-syn thymine dimer on the template |
|
Classification
|
TRANSFERASE/ELECTRON TRANSPORT/DNA |
|
Compound
|
5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*AP*C*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*(2DT))-3' |
|
Source
|
null (1SKS) |
|
|
Sequence
|
B: |
KIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPIL
DEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFK
NGEVAATKVGALSKGQLKEFLDANL
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
70 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
N6-acetyllysine => ECO:0000269|PubMed:18723842
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
2)
|
chain |
B |
| residue |
24-42 |
| type |
prosite |
| sequence |
LVDFWAEWCGPCKMIAPIL
|
| description |
THIOREDOXIN_1 Thioredoxin family active site. LVdFWaeWCGPCKmIapiL
|
| source |
prosite : PS00194
|
|
|
3)
|
chain |
B |
| residue |
33 |
| type |
ACT_SITE |
| sequence |
G
|
| description |
Nucleophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
B |
| residue |
36 |
| type |
ACT_SITE |
| sequence |
K
|
| description |
Nucleophile
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
B |
| residue |
27 |
| type |
SITE |
| sequence |
F
|
| description |
Deprotonates C-terminal active site Cys
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
B |
| residue |
34 |
| type |
SITE |
| sequence |
P
|
| description |
Contributes to redox potential value
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
B |
| residue |
35 |
| type |
SITE |
| sequence |
C
|
| description |
Contributes to redox potential value
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|