eF-site ID 1skb-A PDB Code 1skb Chain A click to enlarge Title Crystallographic snapshots of Aspergillus fumigatus phytase revealing its enzymatic dynamics Classification HYDROLASE Compound 3-phytase A Source Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) (PHYA_ASPFU) Sequence A:  CDTVDLGYQCSPATSHLWGQYSPFFSLEDELSVSSKLPKD CRITLVQVLSRHGARYPTSSKSKKYKKLVTAIQANATDFK GKFAFLKTYNYTLGADDLTPFGEQQLVNSGIKFYQRYKAL ARSVVPFIRASGSDRVIASGEKFIEGFQQAKLADPGATNR AAPAISVIIPESETFNNTLDHGVCTKFEASQLGDEVAANF TALFAPDIRARAEKHLPGVTLTDEDVVSLMDMCSFDTVAR TSDASQLSPFCQLFTHNEWKKYNYLQSLGKYYGYGAGNPL GPAQGIGFTNELIARLTRSPVQDHTSTNSTLVSNPATFPL NATMYVDFSHDNSMVSIFFALGLYNGTEPLSRTSVESAKE LDGYSASWVVPFGARAYFETMQCKSEKEPLVRALINDRVV PLHGCDVDKLGRCKLNDFVKGLSWARSGGNWGECF Description (1)  3-phytase A (E.C.3.1.3.8) Functional site 1) chain A residue 50-64 type prosite sequence ITLVQVLSRHGARYP description HIS_ACID_PHOSPHAT_1 Histidine acid phosphatases phosphohistidine signature. ItlVqvLsRHGaRyP source prosite : PS00616 2) chain A residue 332-348 type prosite sequence MYVDFSHDNSMVSIFFA description HIS_ACID_PHOSPHAT_2 Histidine acid phosphatases active site signature. MyVDfSHDNSMvsIffA source prosite : PS00778 3) chain A residue 82 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15136045, ECO:0000269|PubMed:15341723, ECO:0007744|PDB:1QWO, ECO:0007744|PDB:1SKB source Swiss-Prot : SWS_FT_FI5 4) chain A residue 184 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15136045, ECO:0000269|PubMed:15341723, ECO:0007744|PDB:1QWO, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9, ECO:0007744|PDB:1SKA, ECO:0007744|PDB:1SKB source Swiss-Prot : SWS_FT_FI6 5) chain A residue 207 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15136045, ECO:0000269|PubMed:15341723, ECO:0007744|PDB:1QWO, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9, ECO:0007744|PDB:1SKA, ECO:0007744|PDB:1SKB source Swiss-Prot : SWS_FT_FI6 6) chain A residue 316 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15136045, ECO:0000269|PubMed:15341723, ECO:0007744|PDB:1QWO, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9, ECO:0007744|PDB:1SKA, ECO:0007744|PDB:1SKB source Swiss-Prot : SWS_FT_FI6 7) chain A residue 353 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15136045, ECO:0000269|PubMed:15341723, ECO:0007744|PDB:1QWO, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9, ECO:0007744|PDB:1SKA, ECO:0007744|PDB:1SKB source Swiss-Prot : SWS_FT_FI6 8) chain A residue 329 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:15136045, ECO:0007744|PDB:1QWO source Swiss-Prot : SWS_FT_FI7 9) chain A residue 59 type ACT_SITE sequence H description Nucleophile => ECO:0000269|PubMed:15136045, ECO:0007744|PDB:1QWO source Swiss-Prot : SWS_FT_FI1 10) chain A residue 27 type BINDING sequence Q description BINDING => ECO:0000305|PubMed:15341723, ECO:0007744|PDB:1SK8 source Swiss-Prot : SWS_FT_FI2 11) chain A residue 28 type BINDING sequence Y description BINDING => ECO:0000305|PubMed:15341723, ECO:0007744|PDB:1SK8 source Swiss-Prot : SWS_FT_FI2 12) chain A residue 278 type BINDING sequence K description BINDING => ECO:0000305|PubMed:15341723, ECO:0007744|PDB:1SK8 source Swiss-Prot : SWS_FT_FI2 13) chain A residue 58 type BINDING sequence R description BINDING => ECO:0000305|PubMed:15341723, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9 source Swiss-Prot : SWS_FT_FI3 14) chain A residue 62 type BINDING sequence R description BINDING => ECO:0000305|PubMed:15341723, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9 source Swiss-Prot : SWS_FT_FI3 15) chain A residue 142 type BINDING sequence R description BINDING => ECO:0000305|PubMed:15341723, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9 source Swiss-Prot : SWS_FT_FI3 16) chain A residue 338 type BINDING sequence H description BINDING => ECO:0000305|PubMed:15341723, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9 source Swiss-Prot : SWS_FT_FI3 17) chain A residue 339 type BINDING sequence D description BINDING => ECO:0000305|PubMed:15341723, ECO:0007744|PDB:1SK8, ECO:0007744|PDB:1SK9 source Swiss-Prot : SWS_FT_FI3 18) chain A residue 59 type BINDING sequence H description BINDING => ECO:0000250|UniProtKB:P34752 source Swiss-Prot : SWS_FT_FI4 19) chain A residue 65 type BINDING sequence T description BINDING => ECO:0000250|UniProtKB:P34752 source Swiss-Prot : SWS_FT_FI4 20) chain A residue 188 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:P34752 source Swiss-Prot : SWS_FT_FI4

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