eF-site ID 1shv-A PDB Code 1shv Chain A click to enlarge Title STRUCTURE OF SHV-1 BETA-LACTAMASE Classification HYDROLASE Compound PROTEIN (BETA-LACTAMASE SHV-1) Source (BLA1_ECOLI) Sequence A:  SPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADER FPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDY SPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGP AGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPAS MAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVL PAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRD TPASMAERNQQIAGIGAALIEHWQR Description Functional site 1) chain A residue 70 type sequence S description CATALYTIC SITE source : CAT 2) chain A residue 73 type sequence K description CATALYTIC SITE source : CAT 3) chain A residue 166 type sequence E description CATALYTIC SITE source : CAT 4) chain A residue 130 type sequence S description CATALYTIC SITE source : CAT 5) chain A residue 93 type sequence R description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 6) chain A residue 94 type sequence K description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 7) chain A residue 95 type sequence I description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 8) chain A residue 96 type sequence H description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 9) chain A residue 224 type sequence V description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 10) chain A residue 226 type sequence P description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 11) chain A residue 246 type sequence I description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 12) chain A residue 248 type sequence A description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 13) chain A residue 261 type sequence V description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 14) chain A residue 263 type sequence I description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 15) chain A residue 280 type sequence A description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 16) chain A residue 283 type sequence G description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 17) chain A residue 287 type sequence I description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 18) chain A residue 288 type sequence E description BINDING SITE FOR RESIDUE MA4 A 300 source : AC1 19) chain A residue 66-81 type prosite sequence FPMMSTFKVVLCGAVL description BETA_LACTAMASE_A Beta-lactamase class-A active site. FpMMSTfKvvlCGAVL source prosite : PS00146 20) chain A residue 70 type ACT_SITE sequence S description Acyl-ester intermediate source Swiss-Prot : SWS_FT_FI1 21) chain A residue 168 type ACT_SITE sequence E description Proton acceptor source Swiss-Prot : SWS_FT_FI2 22) chain A residue 234 type BINDING sequence K description source Swiss-Prot : SWS_FT_FI3

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