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|
eF-site ID
|
1shc-AB |
|
PDB Code
|
1shc |
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Chain
|
A, B |
|
click to enlarge
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Title
|
SHC PTB DOMAIN COMPLEXED WITH A TRKA RECEPTOR PHOSPHOPEPTIDE, NMR, MINIMIZED AVERAGE STRUCTURE |
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Classification
|
COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) |
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Compound
|
SHC |
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Source
|
Homo sapiens (Human) (NTRK1_HUMAN) |
|
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Sequence
|
A: |
GSHMGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSY
LVRYMGCVEVLQSMRALDFNTRTQVTREAISLVCEAVPGA
KGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSSLN
LMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPV
NQRACHILECPEGLAQDVISTIGQAFELRFKQYLR
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| B: |
HIIENPQXFSDA
|
|
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Description
|
|
Functional site
|
|
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1)
|
chain |
B |
| residue |
490 |
| type |
SITE |
| sequence |
X
|
| description |
Interaction with SHC1
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
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2)
|
chain |
B |
| residue |
490 |
| type |
MOD_RES |
| sequence |
X
|
| description |
Phosphotyrosine; by autocatalysis => ECO:0000269|PubMed:15488758, ECO:0000269|PubMed:27676246, ECO:0000269|PubMed:8155326
|
| source |
Swiss-Prot : SWS_FT_FI2
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