eF-site ID 1sfj-A
PDB Code 1sfj
Chain A

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Title 2.4A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, with 3-dehydroquinate bound
Classification LYASE
Compound 3-dehydroquinate dehydratase
Source Staphylococcus aureus (strain MRSA252) (AROD_STAAR)
Sequence A:  HVEVVATITPQETLIQKINHRIDAIDVLELRIDQFENVTV
DQVAEMITKLSFKLLVTYRTKLQGGYGQFTNDSYLNLISD
LANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVIIS
HHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDV
LNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGA
LTYGCIGEPQAPGQIDVTDLKAQVTLY
Description


Functional site

1) chain A
residue 9
type
sequence T
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

2) chain A
residue 35
type
sequence E
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

3) chain A
residue 37
type
sequence R
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

4) chain A
residue 70
type
sequence R
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

5) chain A
residue 133
type
sequence H
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

6) chain A
residue 160
type
sequence K
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

7) chain A
residue 202
type
sequence R
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

8) chain A
residue 214
type
sequence Y
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

9) chain A
residue 222
type
sequence A
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

10) chain A
residue 225
type
sequence Q
description BINDING SITE FOR RESIDUE DHK A 239
source : AC1

11) chain A
residue 133
type ACT_SITE
sequence H
description Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_00214, ECO:0000269|PubMed:15229896
source Swiss-Prot : SWS_FT_FI1

12) chain A
residue 160
type ACT_SITE
sequence K
description Schiff-base intermediate with substrate => ECO:0000255|HAMAP-Rule:MF_00214, ECO:0000269|PubMed:15229896
source Swiss-Prot : SWS_FT_FI2

13) chain A
residue 35
type BINDING
sequence E
description BINDING => ECO:0000255|HAMAP-Rule:MF_00214
source Swiss-Prot : SWS_FT_FI3

14) chain A
residue 70
type BINDING
sequence R
description BINDING => ECO:0000255|HAMAP-Rule:MF_00214, ECO:0000269|PubMed:15229896
source Swiss-Prot : SWS_FT_FI4

15) chain A
residue 202
type BINDING
sequence R
description BINDING => ECO:0000255|HAMAP-Rule:MF_00214, ECO:0000269|PubMed:15229896
source Swiss-Prot : SWS_FT_FI4

16) chain A
residue 225
type BINDING
sequence Q
description BINDING => ECO:0000255|HAMAP-Rule:MF_00214, ECO:0000269|PubMed:15229896
source Swiss-Prot : SWS_FT_FI4


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