|
|
eF-site ID
|
1sfe-A |
|
PDB Code
|
1sfe |
|
Chain
|
A |
|
click to enlarge
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Title
|
ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI |
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Classification
|
DNA BINDING PROTEIN |
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Compound
|
ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE |
|
Source
|
Escherichia coli (strain K12) (ADA_ECOLI) |
|
|
Sequence
|
A: |
LAVRYALADCELGRCLVAESERGICAILLGDDDATLISEL
QQMFPAADNAPADLMFQQHVREVIASLNQRDTPLTLPLDI
RGTAFQQQVWQALRTIPCGETVSYQQLANAIGKPKAVRAV
ASACAANKLAIVIPCHRVVRGDGSLSGYRWGVSRKAQLLR
REAEN
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
144-150 |
| type |
prosite |
| sequence |
IPCHRVV
|
| description |
MGMT Methylated-DNA--protein-cysteine methyltransferase active site. IPCHRVV
|
| source |
prosite : PS00374
|
|
|
2)
|
chain |
A |
| residue |
146 |
| type |
ACT_SITE |
| sequence |
C
|
| description |
Nucleophile; methyl group acceptor from either O6-methylguanine or O4-methylthymine => ECO:0000255|PROSITE-ProRule:PRU10017, ECO:0000269|PubMed:16209950
|
| source |
Swiss-Prot : SWS_FT_FI1
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