|
|
eF-site ID
|
1seb-A |
|
PDB Code
|
1seb |
|
Chain
|
A |
|
click to enlarge
|
|
|
Title
|
COMPLEX OF THE HUMAN MHC CLASS II GLYCOPROTEIN HLA-DR1 AND THE BACTERIAL SUPERANTIGEN SEB |
|
Classification
|
COMPLEX (MHC II/PEPTIDE/TOXIN) |
|
Compound
|
HLA CLASS II HISTOCOMPATIBILITY ANTIGEN |
|
Source
|
ORGANISM_COMMON: human; ORGANISM_SCIENTIFIC: Homo sapiens; |
|
|
Sequence
|
A: |
IKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKE
TVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYT
PITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVT
WLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDV
YDCRVEHWGLDEPLLKHWEFD
|
|
|
Description
|
(1) |
HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ENDOGENOUS PEPTIDE MODEL, POLY-ALA, ENTEROTOXIN TYPE B
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
55 |
| type |
SITE |
| sequence |
E
|
| description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:23260142, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
2)
|
chain |
A |
| residue |
62 |
| type |
SITE |
| sequence |
N
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
3)
|
chain |
A |
| residue |
69 |
| type |
SITE |
| sequence |
N
|
| description |
Pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI7
|
|
|
4)
|
chain |
A |
| residue |
76 |
| type |
SITE |
| sequence |
R
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:23260142, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819, ECO:0007744|PDB:4FQX, ECO:0007744|PDB:4GBX
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
|
5)
|
chain |
A |
| residue |
78 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
| source |
Swiss-Prot : SWS_FT_FI9
|
|
|
6)
|
chain |
A |
| residue |
118 |
| type |
CARBOHYD |
| sequence |
N
|
| description |
N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:7477400
|
| source |
Swiss-Prot : SWS_FT_FI9
|
|
|
7)
|
chain |
A |
| residue |
53 |
| type |
SITE |
| sequence |
S
|
| description |
Self- and pathogen-derived peptide antigen => ECO:0000269|PubMed:17583734, ECO:0000269|PubMed:21115828, ECO:0000269|PubMed:31619516, ECO:0000269|PubMed:8145819
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
8)
|
chain |
A |
| residue |
161-167 |
| type |
prosite |
| sequence |
YDCRVEH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YDCRVEH
|
| source |
prosite : PS00290
|
|
|
|