eF-site ID 1s26-B PDB Code 1s26 Chain B click to enlarge Title Structure of Anthrax Edema Factor-Calmodulin-alpha,beta-methyleneadenosine 5'-triphosphate Complex Reveals an Alternative Mode of ATP Binding to the Catalytic Site Classification TOXIN,LYASE/METAL BINDING PROTEIN Compound Calmodulin-sensitive adenylate cyclase Source (CALM_HUMAN) Sequence B:  DVLKGEKALKASGLVPEHADAFKKIARELNTYILFRPVNK LATNLIKSGVATKGLNVHGKSSDWGPVAGYIPFDQDLSKK HGQQLAVEKGNLENKKSITEHEGEIGKIPLKLDHLRIEEL KENGIILKGKKEIDNGKKYYLLESNNQVYEFRISDENNEV QYKTKEGKITVLGEKFNWRNIEVMAKNVEGVLKPLTADYD LFALAPSLTEIKKQIPQKEWDKVVNTPNEKQKGVTNLLIK YGIERKPDSTKGTLSNWQKQMLDRLNEAVKYTGYTGGDVV NHGTEQDNEEFPEKDNEIFIINPEGEFILTKNWEMTGRFI EKNITGKDYLYYFNRSYNKIAPGNKAYIEWTDPITKAKIN TIPSVKKIAGYLSDYYNSANHIFSQEKKRKISIFRGIQAY NEIENVLKSKQIAPEYKNYFQYLKERITNQVQLLLTHQKF KLLYKQLNFTENETDNFEVFQKIID Description Functional site 1) chain B residue 491 type sequence D description BINDING SITE FOR RESIDUE YB B 902 source : AC8 2) chain B residue 493 type sequence D description BINDING SITE FOR RESIDUE YB B 902 source : AC8 3) chain B residue 577 type sequence H description BINDING SITE FOR RESIDUE YB B 902 source : AC8 4) chain B residue 329 type sequence R description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 5) chain B residue 346 type sequence K description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 6) chain B residue 351 type sequence H description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 7) chain B residue 352 type sequence G description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 8) chain B residue 354 type sequence S description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 9) chain B residue 372 type sequence K description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 10) chain B residue 382 type sequence K description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 11) chain B residue 490 type sequence A description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 12) chain B residue 491 type sequence D description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 13) chain B residue 493 type sequence D description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 14) chain B residue 583 type sequence N description BINDING SITE FOR RESIDUE APC B 2139 source : BC2 15) chain B residue 586 type sequence F description BINDING SITE FOR RESIDUE APC B 2139 source : BC2

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