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eF-site ID
|
1rzg-ABCD |
|
PDB Code
|
1rzg |
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Chain
|
A, B, C, D |
|
click to enlarge
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Title
|
Crystal structure of Human anti-HIV-1 GP120 reactive antibody 412d |
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Classification
|
IMMUNE SYSTEM |
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Compound
|
Fab 412d light chain |
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Source
|
(1RZG) |
|
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Sequence
|
A: |
EVQLVQSGAEVKKPGSSVKVSCKASGGTFSNYAINWVRQA
PGQGLEWMGGIIPIFNIAHYAQRFQGRVSITADESTSTAY
MELSSLRSEDTAVFYCASPYPNDXGMSWYFDLWGRGTLVT
VSPASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPV
TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLG
TQTYICNVNHKPSNTKVDKKVEPK
|
| B: |
DIQMTQSPSTLSASVGDRVTITCRASQSISNWLAWYQQKP
GRAPKLLMYKASSLKSGVPSRFSGSGSGTEFTLTISSLQS
DDFATYYCQQHDSSPYTFGQGTKLEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKLYACEVTHQG
LSSPVTKSFNRGE
|
| C: |
VQLVQSGAEVKKPGSSVKVSCKASGGTFSNYAINWVRQAP
GQGLEWMGGIIPIFNIAHYAQRFQGRVSITADESTSTAYM
ELSSLRSEDTAVFYCASPYPNDXGMSWYFDLWGRGTLVTV
SPASTKGPSVFPLAPTAALGCLVKDYFPEPVTVSWNSGAL
TSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVN
HKPSNTKVDKKVEP
|
| D: |
DIQMTQSPSTLSASVGDRVTITCRASQSISNWLAWYQQKP
GRAPKLLMYKASSLKSGVPSRFSGSGSGTEFTLTISSLQS
DDFATYYCQQHDSSPYTFGQGTKLEIKRTVAAPSVFIFPP
SDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKLYACEVTHQG
LSSPVTKSFNRGEC
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
B |
| residue |
192-198 |
| type |
prosite |
| sequence |
YACEVTH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
|
|
2)
|
chain |
A |
| residue |
194-200 |
| type |
prosite |
| sequence |
YICNVNH
|
| description |
IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH
|
| source |
prosite : PS00290
|
|
|
|