eF-site ID 1rzf-L
PDB Code 1rzf
Chain L

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Title Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51
Classification IMMUNE SYSTEM
Compound Fab E51 light chain
Source (1RZF)
Sequence L:  QSILTQPPSVSAAPGQKVTISCSGSSSNIGNNDVSWYQQF
PGTVPKLVIYENNERPSGIPDRFSGSKSGTSATLGITGLQ
TGDEADYYCGTWDSSLSAVVFGGGSKVTVLGQPKAAPSVT
LFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVK
AGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVT
HEGSTVEKTVAPT
Description


Functional site

1) chain L
residue 113
type
sequence A
description BINDING SITE FOR RESIDUE GOL L 9001
source : AC1

2) chain L
residue 198
type
sequence H
description BINDING SITE FOR RESIDUE GOL L 9001
source : AC1

3) chain L
residue 201
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9001
source : AC1

4) chain L
residue 37
type
sequence Q
description BINDING SITE FOR RESIDUE GOL L 9002
source : AC2

5) chain L
residue 45
type
sequence K
description BINDING SITE FOR RESIDUE GOL L 9002
source : AC2

6) chain L
residue 59
type
sequence P
description BINDING SITE FOR RESIDUE GOL L 9002
source : AC2

7) chain L
residue 61
type
sequence R
description BINDING SITE FOR RESIDUE GOL L 9002
source : AC2

8) chain L
residue 62
type
sequence F
description BINDING SITE FOR RESIDUE GOL L 9002
source : AC2

9) chain L
residue 81
type
sequence G
description BINDING SITE FOR RESIDUE GOL L 9002
source : AC2

10) chain L
residue 82
type
sequence D
description BINDING SITE FOR RESIDUE GOL L 9002
source : AC2

11) chain L
residue 115
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9003
source : AC3

12) chain L
residue 117
type
sequence T
description BINDING SITE FOR RESIDUE GOL L 9003
source : AC3

13) chain L
residue 136
type
sequence L
description BINDING SITE FOR RESIDUE GOL L 9003
source : AC3

14) chain L
residue 137
type
sequence I
description BINDING SITE FOR RESIDUE GOL L 9003
source : AC3

15) chain L
residue 138
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9003
source : AC3

16) chain L
residue 105
type
sequence T
description BINDING SITE FOR RESIDUE GOL L 9004
source : AC4

17) chain L
residue 106
type
sequence V
description BINDING SITE FOR RESIDUE GOL L 9004
source : AC4

18) chain L
residue 107
type
sequence L
description BINDING SITE FOR RESIDUE GOL L 9004
source : AC4

19) chain L
residue 108
type
sequence G
description BINDING SITE FOR RESIDUE GOL L 9004
source : AC4

20) chain L
residue 109
type
sequence Q
description BINDING SITE FOR RESIDUE GOL L 9004
source : AC4

21) chain L
residue 111
type
sequence K
description BINDING SITE FOR RESIDUE GOL L 9004
source : AC4

22) chain L
residue 142
type
sequence P
description BINDING SITE FOR RESIDUE GOL L 9004
source : AC4

23) chain L
residue 144
type
sequence A
description BINDING SITE FOR RESIDUE GOL L 9005
source : AC5

24) chain L
residue 145
type
sequence V
description BINDING SITE FOR RESIDUE GOL L 9005
source : AC5

25) chain L
residue 146
type
sequence T
description BINDING SITE FOR RESIDUE GOL L 9005
source : AC5

26) chain L
residue 197
type
sequence T
description BINDING SITE FOR RESIDUE GOL L 9005
source : AC5

27) chain L
residue 199
type
sequence E
description BINDING SITE FOR RESIDUE GOL L 9005
source : AC5

28) chain L
residue 200
type
sequence G
description BINDING SITE FOR RESIDUE GOL L 9005
source : AC5

29) chain L
residue 54
type
sequence R
description BINDING SITE FOR RESIDUE GOL L 9010
source : AC6

30) chain L
residue 55
type
sequence P
description BINDING SITE FOR RESIDUE GOL L 9010
source : AC6

31) chain L
residue 56
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9010
source : AC6

32) chain L
residue 57
type
sequence G
description BINDING SITE FOR RESIDUE GOL L 9010
source : AC6

33) chain L
residue 58
type
sequence I
description BINDING SITE FOR RESIDUE GOL L 9010
source : AC6

34) chain L
residue 159
type
sequence G
description BINDING SITE FOR RESIDUE GOL L 9010
source : AC6

35) chain L
residue 160
type
sequence V
description BINDING SITE FOR RESIDUE GOL L 9010
source : AC6

36) chain L
residue 161
type
sequence E
description BINDING SITE FOR RESIDUE GOL L 9010
source : AC6

37) chain L
residue 110
type
sequence P
description BINDING SITE FOR RESIDUE GOL L 9011
source : AC7

38) chain L
residue 141
type
sequence Y
description BINDING SITE FOR RESIDUE GOL L 9011
source : AC7

39) chain L
residue 171
type
sequence N
description BINDING SITE FOR RESIDUE GOL L 9011
source : AC7

40) chain L
residue 65
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9012
source : AC8

41) chain L
residue 66
type
sequence K
description BINDING SITE FOR RESIDUE GOL L 9012
source : AC8

42) chain L
residue 67
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9012
source : AC8

43) chain L
residue 70
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9012
source : AC8

44) chain L
residue 71
type
sequence A
description BINDING SITE FOR RESIDUE GOL L 9012
source : AC8

45) chain L
residue 72
type
sequence T
description BINDING SITE FOR RESIDUE GOL L 9012
source : AC8

46) chain L
residue 18
type
sequence K
description BINDING SITE FOR RESIDUE GOL L 9013
source : AC9

47) chain L
residue 20
type
sequence T
description BINDING SITE FOR RESIDUE GOL L 9013
source : AC9

48) chain L
residue 63
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9013
source : AC9

49) chain L
residue 64
type
sequence G
description BINDING SITE FOR RESIDUE GOL L 9013
source : AC9

50) chain L
residue 65
type
sequence S
description BINDING SITE FOR RESIDUE GOL L 9013
source : AC9

51) chain L
residue 38
type
sequence Q
description BINDING SITE FOR RESIDUE IPA L 7001
source : BC1

52) chain L
residue 41
type
sequence G
description BINDING SITE FOR RESIDUE IPA L 7001
source : BC1

53) chain L
residue 85
type
sequence D
description BINDING SITE FOR RESIDUE IPA L 7002
source : BC2

54) chain L
residue 87
type
sequence Y
description BINDING SITE FOR RESIDUE IPA L 7002
source : BC2

55) chain L
residue 100
type
sequence G
description BINDING SITE FOR RESIDUE IPA L 7002
source : BC2

56) chain L
residue 32
type
sequence D
description BINDING SITE FOR RESIDUE GOL H 9006
source : BC3

57) chain L
residue 34
type
sequence S
description BINDING SITE FOR RESIDUE GOL H 9006
source : BC3

58) chain L
residue 36
type
sequence Y
description BINDING SITE FOR RESIDUE GOL H 9006
source : BC3

59) chain L
residue 89
type
sequence G
description BINDING SITE FOR RESIDUE GOL H 9006
source : BC3

60) chain L
residue 90
type
sequence T
description BINDING SITE FOR RESIDUE GOL H 9006
source : BC3

61) chain L
residue 96
type
sequence V
description BINDING SITE FOR RESIDUE GOL H 9006
source : BC3

62) chain L
residue 201
type
sequence S
description BINDING SITE FOR RESIDUE GOL H 9007
source : BC4

63) chain L
residue 203
type
sequence V
description BINDING SITE FOR RESIDUE GOL H 9007
source : BC4

64) chain L
residue 192-198
type prosite
sequence YSCQVTH
description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
source prosite : PS00290


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