eF-site ID 1rzf-H PDB Code 1rzf Chain H click to enlarge Title Crystal structure of Human anti-HIV-1 GP120-reactive antibody E51 Classification IMMUNE SYSTEM Compound Fab E51 light chain Source (1RZF) Sequence H:  VQLVQSGAEVNKPGSSVKVSCQASGATLNSHAFSWVRQAP GQGLEWMAGIIPIFGSSHYAQKFRGRVTISADESTRTVYL HLRGLRSDDTAVYYCASNSIAGGYYYDMDVWGQGTTVTVS SASTKGPSVFPLAPTSGGTAALGCLVKDYFPEPVTVSWNS GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYIC NVNHKPSNTKVDKRVEPK Description Functional site 1) chain H residue 209 type sequence K description BINDING SITE FOR RESIDUE GOL L 9001 source : AC1 2) chain H residue 183 type sequence T description BINDING SITE FOR RESIDUE GOL L 9003 source : AC3 3) chain H residue 172 type sequence S description BINDING SITE FOR RESIDUE GOL L 9010 source : AC6 4) chain H residue 53 type sequence I description BINDING SITE FOR RESIDUE GOL L 9012 source : AC8 5) chain H residue 54 type sequence F description BINDING SITE FOR RESIDUE GOL L 9013 source : AC9 6) chain H residue 43 type sequence Q description BINDING SITE FOR RESIDUE IPA L 7002 source : BC2 7) chain H residue 44 type sequence G description BINDING SITE FOR RESIDUE IPA L 7002 source : BC2 8) chain H residue 120 type sequence S description BINDING SITE FOR RESIDUE GOL H 9007 source : BC4 9) chain H residue 121 type sequence V description BINDING SITE FOR RESIDUE GOL H 9007 source : BC4 10) chain H residue 209 type sequence K description BINDING SITE FOR RESIDUE GOL H 9007 source : BC4 11) chain H residue 38 type sequence R description BINDING SITE FOR RESIDUE GOL H 9008 source : BC5 12) chain H residue 39 type sequence Q description BINDING SITE FOR RESIDUE GOL H 9008 source : BC5 13) chain H residue 40 type sequence A description BINDING SITE FOR RESIDUE GOL H 9008 source : BC5 14) chain H residue 43 type sequence Q description BINDING SITE FOR RESIDUE GOL H 9008 source : BC5 15) chain H residue 44 type sequence G description BINDING SITE FOR RESIDUE GOL H 9008 source : BC5 16) chain H residue 46 type sequence E description BINDING SITE FOR RESIDUE GOL H 9008 source : BC5 17) chain H residue 45 type sequence L description BINDING SITE FOR RESIDUE GOL H 9009 source : BC6 18) chain H residue 46 type sequence E description BINDING SITE FOR RESIDUE GOL H 9009 source : BC6 19) chain H residue 194-200 type prosite sequence YICNVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YSCQVTH source prosite : PS00290

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