eF-site ID 1rwe-ABCD PDB Code 1rwe Chain A, B, C, D click to enlarge Title Enhancing the activity of insulin at receptor edge: crystal structure and photo-cross-linking of A8 analogues Classification HORMONE/GROWTH FACTOR Compound insulin Source Homo sapiens (Human) (INS_HUMAN) Sequence A:  GIVEQCCHSICSLYQLENYCN B:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT C:  GIVEQCCHSICSLYQLENYCN D:  FVNQHLCGSHLVEALYLVCGERGFFYTPKT Description Functional site 1) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 201 source : AC1 2) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 201 source : AC1 3) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN B 201 source : AC1 4) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 301 source : AC2 5) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 301 source : AC2 6) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE ZN D 301 source : AC2 7) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 202 source : AC3 8) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 202 source : AC3 9) chain B residue 10 type sequence H description BINDING SITE FOR RESIDUE CL B 202 source : AC3 10) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE CL D 302 source : AC4 11) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE CL D 302 source : AC4 12) chain D residue 10 type sequence H description BINDING SITE FOR RESIDUE CL D 302 source : AC4 13) chain C residue 6 type sequence C description BINDING SITE FOR RESIDUE IPH C 200 source : AC5 14) chain C residue 10 type sequence I description BINDING SITE FOR RESIDUE IPH C 200 source : AC5 15) chain C residue 11 type sequence C description BINDING SITE FOR RESIDUE IPH C 200 source : AC5 16) chain D residue 5 type sequence H description BINDING SITE FOR RESIDUE IPH C 200 source : AC5 17) chain D residue 11 type sequence L description BINDING SITE FOR RESIDUE IPH C 200 source : AC5 18) chain A residue 6-20 type prosite sequence CCHSICSLYQLENYC description INSULIN Insulin family signature. CCHSiCSlyqLenyC source prosite : PS00262

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