|
|
eF-site ID
|
1rqc-G |
|
PDB Code
|
1rqc |
|
Chain
|
G |
|
click to enlarge
|
|
|
Title
|
Crystals of peptide deformylase from Plasmodium falciparum with ten subunits per asymmetric unit reveal critical characteristics of the active site for drug design |
|
Classification
|
HYDROLASE |
|
Compound
|
formylmethionine deformylase |
|
Source
|
Plasmodium falciparum (isolate 3D7) (Q8I372_PLAF7) |
|
|
Sequence
|
G: |
KIVKYPDPILRRRSEEVTNFDDNLKRVVRKXFDIXYESKG
IGLSAPQVNISKRIIVWNALYEKRKEENERIFINPSIVEQ
SLVKLKLIEGCLSFPGIEGKVERPSIVSISYYDINGYKHL
KILKGIHSRIFQHEFDHLNGTLFIDKXTQVDKKKVRPKLN
ELIRDYKATHS
|
|
|
Description
|
(1) |
formylmethionine deformylase
|
|
Functional site
|
|
|
1)
|
chain |
G |
| residue |
112 |
| type |
|
| sequence |
Q
|
| description |
BINDING SITE FOR RESIDUE CO G 361
|
| source |
: AC7
|
|
|
2)
|
chain |
G |
| residue |
156 |
| type |
|
| sequence |
C
|
| description |
BINDING SITE FOR RESIDUE CO G 361
|
| source |
: AC7
|
|
|
3)
|
chain |
G |
| residue |
198 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE CO G 361
|
| source |
: AC7
|
|
|
4)
|
chain |
G |
| residue |
202 |
| type |
|
| sequence |
H
|
| description |
BINDING SITE FOR RESIDUE CO G 361
|
| source |
: AC7
|
|
|
|