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|
eF-site ID
|
1rkc-AB |
|
PDB Code
|
1rkc |
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Chain
|
A, B |
|
click to enlarge
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Title
|
Human vinculin head (1-258) in complex with talin's vinculin binding site 3 (residues 1944-1969) |
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Classification
|
cell adhesion, structural protein |
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Compound
|
Vinculin |
|
Source
|
Homo sapiens (Human) (TLN1_CHICK) |
|
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Sequence
|
A: |
MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDL
TAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIK
VENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTS
DLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTY
TKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKE
LLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE
INEIIRVLQLTSWDEDAW
|
| B: |
YTKKELIESARKVSEKVSHVLAALQA
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
162-182 |
| type |
prosite |
| sequence |
KNLGPGMTKMAKMIDERQQEL
|
| description |
VINCULIN_1 Vinculin family talin-binding region signature. KnLgpgMtkMakmideRQQEL
|
| source |
prosite : PS00663
|
|
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2)
|
chain |
A |
| residue |
97 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0000250|UniProtKB:P85972
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
173 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
|
| source |
Swiss-Prot : SWS_FT_FI2
|
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