eF-site ID 1rdt-D PDB Code 1rdt Chain D click to enlarge Title Crystal Structure of a new rexinoid bound to the RXRalpha ligand binding doamin in the RXRalpha/PPARgamma heterodimer Classification HORMONE/GROWTH FACTOR Compound Retinoic acid receptor RXR-alpha Source Homo sapiens (Human) (1RDT) Sequence D:  AESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKS PFVIYDMNSLMEVAIRIFQGCQFRSVEAVQEITEYAKSIP GFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEG QGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDL AIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLN HPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMS LHPLLQEIYKDLY Description Functional site 1) chain D residue 282 type sequence F description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 2) chain D residue 284 type sequence G description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 3) chain D residue 285 type sequence C description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 4) chain D residue 286 type sequence Q description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 5) chain D residue 289 type sequence S description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 6) chain D residue 323 type sequence H description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 7) chain D residue 327 type sequence Y description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 8) chain D residue 330 type sequence L description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 9) chain D residue 341 type sequence I description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 10) chain D residue 348 type sequence M description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 11) chain D residue 363 type sequence F description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 12) chain D residue 449 type sequence H description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 13) chain D residue 465 type sequence L description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 14) chain D residue 469 type sequence L description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 15) chain D residue 473 type sequence Y description BINDING SITE FOR RESIDUE 570 D 478 source : AC2 16) chain D residue 323 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 17) chain D residue 449 type MOD_RES sequence H description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 18) chain D residue 473 type MOD_RES sequence Y description Phosphoserine => ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 19) chain D residue 224 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:36737649 source Swiss-Prot : SWS_FT_FI2

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