eF-site ID 1rdt-A PDB Code 1rdt Chain A click to enlarge Title Crystal Structure of a new rexinoid bound to the RXRalpha ligand binding doamin in the RXRalpha/PPARgamma heterodimer Classification HORMONE/GROWTH FACTOR Compound Retinoic acid receptor RXR-alpha Source Homo sapiens (Human) (1RDT) Sequence A:  EDMPVERILEAELAVEPDPVTNICQAADKQLFTLVEWAKR IPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGIL LATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKT ELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCK HKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDT PIDTFLMEMLE Description Functional site 1) chain A residue 268 type sequence I description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 2) chain A residue 271 type sequence A description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 3) chain A residue 272 type sequence A description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 4) chain A residue 275 type sequence Q description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 5) chain A residue 306 type sequence N description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 6) chain A residue 309 type sequence L description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 7) chain A residue 313 type sequence F description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 8) chain A residue 316 type sequence R description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 9) chain A residue 326 type sequence L description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 10) chain A residue 327 type sequence A description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 11) chain A residue 345 type sequence I description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 12) chain A residue 346 type sequence F description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 13) chain A residue 435 type sequence H description BINDING SITE FOR RESIDUE L79 A 463 source : AC1 14) chain A residue 436 type sequence L description BINDING SITE FOR RESIDUE L79 A 463 source : AC1

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