eF-site ID 1ra6-A PDB Code 1ra6 Chain A click to enlarge Title Poliovirus Polymerase Full Length Apo Structure Classification TRANSFERASE Compound Genome polyprotein Source null (POLH_POL1M) Sequence A:  GEIQWMRPSKEVGYPIINAPSKTKLEPSAFHYVFEGVKEP AVLTKNDPRLKTDFEEAIFSKYVGNKITEVDEYMKEAVDH YAGQLMSLDINTEQMXLEDAMYGTDGLEALDLSTSAGYPY VAMGKKKRDILNKQTRDTKEMQKLLDTYGINLPLVTYVKD ELRSKTKVEQGKSRLIEASSLNDSVAMRMAFGNLYAAFHK NPGVITGSAVGXDPDLFWSKIPVLMEEKLFAFDYTGYDAS LSPAWFEALKMVLEKIGFGDRVDYIDYLNHSHHLYKNKTY XVKGGMPSGXSGTSIFNSMINNLIIRTLLLKTYKGIDLDH LKMIAYGDDVIASYPHEVDASLLAQSGKDYGLTMTPADKS ATFETVTWENVTFLKRFFRADEKYPFLIHPVMPMKEIHES IRWTKDPRNTQDHVRSLCLLAWHNGEEEYNKFLAKIRSVP IGRALDLPEYSTLYDRWLDSF Description Functional site 1) chain A residue 28 type sequence S description BINDING SITE FOR RESIDUE ACY A 901 source : AC1 2) chain A residue 401 type sequence I description BINDING SITE FOR RESIDUE ACY A 901 source : AC1 3) chain A residue 403 type sequence W description BINDING SITE FOR RESIDUE ACY A 901 source : AC1 4) chain A residue 404 type sequence T description BINDING SITE FOR RESIDUE ACY A 901 source : AC1 5) chain A residue 410 type sequence T description BINDING SITE FOR RESIDUE ACY A 901 source : AC1 6) chain A residue 413 type sequence H description BINDING SITE FOR RESIDUE ACY A 901 source : AC1 7) chain A residue 71 type sequence D description BINDING SITE FOR RESIDUE ACY A 902 source : AC2 8) chain A residue 311 type sequence K description BINDING SITE FOR RESIDUE ACY A 902 source : AC2 9) chain A residue 349 type sequence D description BINDING SITE FOR RESIDUE ACY A 902 source : AC2 10) chain A residue 350 type sequence Y description BINDING SITE FOR RESIDUE ACY A 902 source : AC2 11) chain A residue 375 type sequence K description BINDING SITE FOR RESIDUE ACY A 903 source : AC3 12) chain A residue 417 type sequence L description BINDING SITE FOR RESIDUE ACY A 903 source : AC3 13) chain A residue 334 type sequence Y description BINDING SITE FOR RESIDUE ACY A 904 source : AC4 14) chain A residue 336 type sequence H description BINDING SITE FOR RESIDUE ACY A 904 source : AC4 15) chain A residue 440 type sequence P description BINDING SITE FOR RESIDUE ACY A 904 source : AC4 16) chain A residue 443 type sequence R description BINDING SITE FOR RESIDUE ACY A 904 source : AC4 17) chain A residue 270 type sequence H description BINDING SITE FOR RESIDUE ACY A 906 source : AC5 18) chain A residue 357 type sequence A description BINDING SITE FOR RESIDUE ACY A 908 source : AC7 19) chain A residue 360 type sequence S description BINDING SITE FOR RESIDUE ACY A 908 source : AC7 20) chain A residue 370 type sequence N description BINDING SITE FOR RESIDUE ACY A 908 source : AC7 21) chain A residue 329 type BINDING sequence D description BINDING => ECO:0000269|PubMed:21148772, ECO:0000305|PubMed:2196557 source Swiss-Prot : SWS_FT_FI2 22) chain A residue 1 type SITE sequence G description Cleavage; by protease 3C => ECO:0000250|UniProtKB:P03301 source Swiss-Prot : SWS_FT_FI3 23) chain A residue 234 type BINDING sequence Y description BINDING => ECO:0000269|PubMed:21148772 source Swiss-Prot : SWS_FT_FI1

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