eF-site ID 1r66-A PDB Code 1r66 Chain A click to enlarge Title Crystal Structure of DesIV (dTDP-glucose 4,6-dehydratase) from Streptomyces venezuelae with NAD and TYD bound Classification LYASE Compound TDP-glucose-4,6-dehydratase Source (Q9ZGH3_9ACTO) Sequence A:  MRLLVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLT YAGNRANLAPVDADPRLRFVHGDIRDAGLLARELRGVDAI VHFAAESHVDRSIAGASVFTETNVQGTQTLLQCAVDAGVG RVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAASKAGSDL VARAYHRTYGLDVRITRCCNNYGPYQHPEKLIPLFVTNLL DGGTLPLYGDGANVREWVHTDDHCRGIALVLAGGRAGEIY HIGGGLELTNRELTGILLDSLGADWSSVRKVADRKGHDLR YSLDGGKIERELGYRPQVSFADGLARTVRWYRENRGWWEP LK Description Functional site 1) chain A residue 144 type sequence P description BINDING SITE FOR RESIDUE CL A 902 source : AC1 2) chain A residue 144 type sequence P description BINDING SITE FOR RESIDUE CL A 902 source : AC1 3) chain A residue 145 type sequence L description BINDING SITE FOR RESIDUE CL A 902 source : AC1 4) chain A residue 145 type sequence L description BINDING SITE FOR RESIDUE CL A 902 source : AC1 5) chain A residue 9 type sequence A description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 6) chain A residue 10 type sequence G description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 7) chain A residue 11 type sequence F description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 8) chain A residue 12 type sequence I description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 9) chain A residue 37 type sequence D description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 10) chain A residue 38 type sequence S description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 11) chain A residue 39 type sequence L description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 12) chain A residue 40 type sequence T description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 13) chain A residue 42 type sequence A description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 14) chain A residue 43 type sequence G description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 15) chain A residue 62 type sequence G description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 16) chain A residue 63 type sequence D description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 17) chain A residue 64 type sequence I description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 18) chain A residue 83 type sequence F description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 19) chain A residue 84 type sequence A description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 20) chain A residue 85 type sequence A description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 21) chain A residue 87 type sequence S description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 22) chain A residue 102 type sequence T description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 23) chain A residue 125 type sequence V description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 24) chain A residue 126 type sequence S description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 25) chain A residue 151 type sequence Y description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 26) chain A residue 155 type sequence K description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 27) chain A residue 178 type sequence C description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 28) chain A residue 179 type sequence C description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 29) chain A residue 180 type sequence N description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 30) chain A residue 181 type sequence N description BINDING SITE FOR RESIDUE NAD A 900 source : AC2 31) chain A residue 88 type sequence H description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 32) chain A residue 89 type sequence V description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 33) chain A residue 129 type sequence E description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 34) chain A residue 180 type sequence N description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 35) chain A residue 189 type sequence E description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 36) chain A residue 190 type sequence K description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 37) chain A residue 191 type sequence L description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 38) chain A residue 194 type sequence L description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 39) chain A residue 206 type sequence P description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 40) chain A residue 208 type sequence Y description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 41) chain A residue 215 type sequence R description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 42) chain A residue 250 type sequence N description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 43) chain A residue 274 type sequence R description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 44) chain A residue 277 type sequence H description BINDING SITE FOR RESIDUE TYD A 901 source : AC3 45) chain A residue 138-166 type prosite sequence SWTESSPLEPNSPYAASKAGSDLVARAYH description ADH_SHORT Short-chain dehydrogenases/reductases family signature. SwtessplepNspYAASKAGSdLVArAYH source prosite : PS00061

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