|
|
eF-site ID
|
1r4n-L |
|
PDB Code
|
1r4n |
|
Chain
|
L |
|
click to enlarge
|
|
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Title
|
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP |
|
Classification
|
CELL CYCLE |
|
Compound
|
amyloid beta precursor protein-binding protein 1 |
|
Source
|
null (NEDD8_HUMAN) |
|
|
Sequence
|
L: |
MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQ
QRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGG
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
L |
| residue |
176 |
| type |
|
| sequence |
G
|
| description |
BINDING SITE FOR RESIDUE ATP H 8
|
| source |
: AC8
|
|
|
2)
|
chain |
L |
| residue |
108 |
| type |
SITE |
| sequence |
L
|
| description |
Interaction with UBE1C => ECO:0000269|PubMed:14690597
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
L |
| residue |
144 |
| type |
SITE |
| sequence |
I
|
| description |
Interaction with UBE1C => ECO:0000269|PubMed:14690597
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
4)
|
chain |
L |
| residue |
140 |
| type |
MOD_RES |
| sequence |
Q
|
| description |
(Microbial infection) Deamidated glutamine => ECO:0000269|PubMed:20688984, ECO:0000269|PubMed:21903097, ECO:0000269|PubMed:23175788, ECO:0000269|PubMed:23589306, ECO:0000269|PubMed:26632597
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
L |
| residue |
148 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine => ECO:0000250|UniProtKB:P29595
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
L |
| residue |
176 |
| type |
CROSSLNK |
| sequence |
G
|
| description |
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
|