eF-site ID 1r4n-I
PDB Code 1r4n
Chain I

click to enlarge
Title APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex with ATP
Classification CELL CYCLE
Compound amyloid beta precursor protein-binding protein 1
Source Homo sapiens (Human) (NEDD8_HUMAN)
Sequence I:  MLIKVKTLTGKEIEIDIEPTDKVERIKERVEEKEGIPPQQ
QRLIYSGKQMNDEKTAADYKILGGSVLHLVLALRGG
Description


Functional site

1) chain I
residue 176
type
sequence G
description BINDING SITE FOR RESIDUE ATP B 5
source : AC5

2) chain I
residue 127-152
type prosite
sequence KERVEEKEGIPPQQQRLIYSGKQMND
description UBIQUITIN_1 Ubiquitin domain signature. KerVeEkegIPpqqQrLIYsGkqmnD
source prosite : PS00299

3) chain I
residue 108
type SITE
sequence L
description Interaction with UBE1C => ECO:0000269|PubMed:14690597
source Swiss-Prot : SWS_FT_FI1

4) chain I
residue 144
type SITE
sequence I
description Interaction with UBE1C => ECO:0000269|PubMed:14690597
source Swiss-Prot : SWS_FT_FI1

5) chain I
residue 140
type MOD_RES
sequence Q
description (Microbial infection) Deamidated glutamine => ECO:0000269|PubMed:20688984, ECO:0000269|PubMed:21903097, ECO:0000269|PubMed:23175788, ECO:0000269|PubMed:23589306, ECO:0000269|PubMed:26632597
source Swiss-Prot : SWS_FT_FI2

6) chain I
residue 148
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:P29595
source Swiss-Prot : SWS_FT_FI3

7) chain I
residue 176
type CROSSLNK
sequence G
description Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
source Swiss-Prot : SWS_FT_FI4


Display surface

Download
Links