eF-site ID 1r4m-H PDB Code 1r4m Chain H click to enlarge Title APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex Classification CELL CYCLE Compound amyloid beta precursor protein-binding protein 1 Source Homo sapiens (Human) (NEDD8_HUMAN) Sequence H:  DWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKV LVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQ FLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFN DTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDP SSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQV NFPMATIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDG DDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPA VASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLY TYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNS ASLQMKSPAITATNRTLYLQSVTSIEERTRKELGLVDGQE AVADVTTPQTVLFKLHFT Description Functional site 1) chain H residue 199 type sequence C description BINDING SITE FOR RESIDUE ZN H 1 source : AC1 2) chain H residue 202 type sequence C description BINDING SITE FOR RESIDUE ZN H 1 source : AC1 3) chain H residue 343 type sequence C description BINDING SITE FOR RESIDUE ZN H 1 source : AC1 4) chain H residue 346 type sequence C description BINDING SITE FOR RESIDUE ZN H 1 source : AC1 5) chain H residue 340 type sequence K description BINDING SITE FOR RESIDUE ZN H 4 source : AC4 6) chain H residue 373 type sequence S description BINDING SITE FOR RESIDUE ZN H 4 source : AC4 7) chain H residue 216 type ACT_SITE sequence A description Glycyl thioester intermediate source Swiss-Prot : SWS_FT_FI1 8) chain H residue 79 type BINDING sequence D description BINDING => ECO:0000269|PubMed:14690597 source Swiss-Prot : SWS_FT_FI2 9) chain H residue 127 type BINDING sequence I description BINDING => ECO:0000269|PubMed:14690597 source Swiss-Prot : SWS_FT_FI2 10) chain H residue 190 type SITE sequence R description Determines specificity for NEDD8 source Swiss-Prot : SWS_FT_FI3

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