|
|
eF-site ID
|
1r4m-D |
|
PDB Code
|
1r4m |
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Chain
|
D |
|
click to enlarge
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Title
|
APPBP1-UBA3-NEDD8, an E1-ubiquitin-like protein complex |
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Classification
|
CELL CYCLE |
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Compound
|
amyloid beta precursor protein-binding protein 1 |
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Source
|
Homo sapiens (Human) (NEDD8_HUMAN) |
|
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Sequence
|
D: |
DWEGRWNHVKKFLERSGPFTHPDFEPSTESLQFLLDTCKV
LVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQ
FLFRPKDIGRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFN
DTFYRQFHIIVCGLDSIIARRWINGMLISLLNYEDGVLDP
SSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQV
NFPMATIASMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDG
DDPEHIQWIFQKSLERASQYNIRGVTYRLTQGVVKRIIPA
VASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLY
TYTFEAERKENCPACSQLPQNIQFSPSAKLQEVLDYLTNS
ASLQMKSPAITATNRTLYLQSVTSIEERTRKELGLVDGQE
AVADVTTPQTVLFKLHFT
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Description
|
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Functional site
|
|
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1)
|
chain |
D |
| residue |
338 |
| type |
|
| sequence |
E
|
| description |
BINDING SITE FOR RESIDUE ZN J 2
|
| source |
: AC2
|
|
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2)
|
chain |
D |
| residue |
216 |
| type |
ACT_SITE |
| sequence |
A
|
| description |
Glycyl thioester intermediate
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
D |
| residue |
79 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:14690597
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
4)
|
chain |
D |
| residue |
127 |
| type |
BINDING |
| sequence |
I
|
| description |
BINDING => ECO:0000269|PubMed:14690597
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
D |
| residue |
190 |
| type |
SITE |
| sequence |
R
|
| description |
Determines specificity for NEDD8
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|