eF-site ID 1r15-D PDB Code 1r15 Chain D click to enlarge Title Aplysia ADP ribosyl cyclase with bound nicotinamide and R5P Classification HYDROLASE Compound ADP-ribosyl cyclase Source Aplysia californica (California sea hare) (NADA_APLCA) Sequence D:  IVPTRELENVFLGRCKDYEITRYLDILPRVRSDCSALWKD FFKAFSFKNPCDLDLGSYKDFFTSAQQQLPKNKVMFWSGV YDEAHDYANTGRKYITLEDTLPGYMLNSLVWCGQRANPGF NEKVCPDFKTCPVQARESFWGMASSSYAHSAEGEVTYMVD GSNPKVPAYRPDSFFGKYELPNLTNKVTRVKVIVLHRLGE KIIEKCGAGSLLDLEKLVKAKHFAFDCVENPRAVLFLLCS DNPNARECRLA Description (1)  ADP-ribosyl cyclase (E.C.3.2.2.5) Functional site 1) chain D residue 98 type sequence E description BINDING SITE FOR RESIDUE NCA D 349 source : AC4 2) chain D residue 107 type sequence N description BINDING SITE FOR RESIDUE NCA D 349 source : AC4 3) chain D residue 140 type sequence W description BINDING SITE FOR RESIDUE NCA D 349 source : AC4 4) chain D residue 110 type sequence V description BINDING SITE FOR RESIDUE NCA D 449 source : AC7 5) chain D residue 111 type sequence W description BINDING SITE FOR RESIDUE NCA D 449 source : AC7 6) chain D residue 136 type sequence R description BINDING SITE FOR RESIDUE NCA D 449 source : AC7 7) chain D residue 139 type sequence F description BINDING SITE FOR RESIDUE NCA D 449 source : AC7 8) chain D residue 140 type sequence W description BINDING SITE FOR RESIDUE NCA D 449 source : AC7 9) chain D residue 77 type sequence W description BINDING SITE FOR RESIDUE N D 1179 source : CC2 10) chain D residue 78 type sequence S description BINDING SITE FOR RESIDUE N D 1179 source : CC2 11) chain D residue 79 type sequence G description BINDING SITE FOR RESIDUE N D 1179 source : CC2 12) chain D residue 97 type sequence L description BINDING SITE FOR RESIDUE N D 1179 source : CC2 13) chain D residue 173 type sequence S description BINDING SITE FOR RESIDUE N D 1179 source : CC2 14) chain D residue 174 type sequence F description BINDING SITE FOR RESIDUE N D 1179 source : CC2 15) chain D residue 179 type sequence E description BINDING SITE FOR RESIDUE N D 1179 source : CC2 16) chain D residue 98 type catalytic sequence E description 607 source MCSA : MCSA4 17) chain D residue 174 type catalytic sequence F description 607 source MCSA : MCSA4 18) chain D residue 179 type catalytic sequence E description 607 source MCSA : MCSA4

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