eF-site ID 1r0x-D PDB Code 1r0x Chain D click to enlarge Title Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP Classification TRANSPORT PROTEIN Compound Cystic fibrosis transmembrane conductance regulator Source (CFTR_MOUSE) Sequence D:  TGIIMENVTAFWEEGFGELLEKFSHLCLVGNPVLKNINLN IEKGEMLAITGSTGSGKTSLLMLILGELEASEGIIKHSGR VSFCSQFSWIMPGTIKENIIFGVSYDEYRYKSVVKACQLQ QDITKFAEQDNTVLGEGGVTLSGGQRARISLARAVYKDAD LYLLDSPFGYLDVFTEEQVFESCVCKLMANKTRILVTSKM EHLRKADKILILHQGSSYFYGTFSELQSLRPDFSSKLMGY DTFDQFTEERRSSILTETLRRFS Description Functional site 1) chain D residue 465 type sequence T description BINDING SITE FOR RESIDUE MG D 14 source : AC4 2) chain D residue 493 type sequence Q description BINDING SITE FOR RESIDUE MG D 14 source : AC4 3) chain D residue 401 type sequence W description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 4) chain D residue 409 type sequence L description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 5) chain D residue 460 type sequence T description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 6) chain D residue 461 type sequence G description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 7) chain D residue 462 type sequence S description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 8) chain D residue 463 type sequence G description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 9) chain D residue 464 type sequence K description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 10) chain D residue 465 type sequence T description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 11) chain D residue 466 type sequence S description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 12) chain D residue 493 type sequence Q description BINDING SITE FOR RESIDUE ATP D 4 source : AC8 13) chain D residue 578 type sequence L description BINDING SITE FOR RESIDUE ACY C 7 source : BC2 14) chain D residue 540 type sequence V description BINDING SITE FOR RESIDUE ACY D 8 source : BC3 15) chain D residue 541 type sequence L description BINDING SITE FOR RESIDUE ACY D 8 source : BC3 16) chain D residue 542 type sequence G description BINDING SITE FOR RESIDUE ACY D 8 source : BC3 17) chain D residue 545 type sequence G description BINDING SITE FOR RESIDUE ACY D 8 source : BC3 18) chain D residue 546 type sequence V description BINDING SITE FOR RESIDUE ACY D 8 source : BC3 19) chain D residue 547 type sequence T description BINDING SITE FOR RESIDUE ACY D 8 source : BC3 20) chain D residue 532 type sequence K description BINDING SITE FOR RESIDUE ACY D 9 source : BC4 21) chain D residue 549 type sequence S description BINDING SITE FOR RESIDUE ACY D 9 source : BC4 22) chain D residue 552 type sequence Q description BINDING SITE FOR RESIDUE ACY D 9 source : BC4 23) chain D residue 524 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI6 24) chain D residue 401 type BINDING sequence W description BINDING => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI1 25) chain D residue 458 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434, ECO:0007744|PDB:1Q3H, ECO:0007744|PDB:1R0X, ECO:0007744|PDB:1R0Z, ECO:0007744|PDB:1R10, ECO:0007744|PDB:1XF9, ECO:0007744|PDB:1XFA, ECO:0007744|PDB:3SI7 source Swiss-Prot : SWS_FT_FI2 26) chain D residue 493 type BINDING sequence Q description BINDING => ECO:0007744|PDB:1Q3H, ECO:0007744|PDB:1R0X, ECO:0007744|PDB:1R0Z, ECO:0007744|PDB:1XFA source Swiss-Prot : SWS_FT_FI3 27) chain D residue 549 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI4 28) chain D residue 660 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI4 29) chain D residue 670 type MOD_RES sequence S description Phosphoserine; by PKA => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI5

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