eF-site ID 1r0x-C PDB Code 1r0x Chain C click to enlarge Title Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP Classification TRANSPORT PROTEIN Compound Cystic fibrosis transmembrane conductance regulator Source (CFTR_MOUSE) Sequence C:  STTGIIMENVTAFWEEGFGELLEKFSHLCLVGNPVLKNIN LNIEKGEMLAITGSTGSGKTSLLMLILGELEASEGIIKHS GRVSFCSQFSWIMPGTIKENIIFGVSYDEYRYKSVVKACQ LQQDITKFAEQDNTVLGEGGVTLSGGQRARISLARAVYKD ADLYLLDSPFGYLDVFTEEQVFESCVCKLMANKTRILVTS KMEHLRKADKILILHQGSSYFYGTFSELQSLRPDFSSKLM GYDTFDQFTEERRSSILTETLRRFS Description Functional site 1) chain C residue 465 type sequence T description BINDING SITE FOR RESIDUE MG C 12 source : AC2 2) chain C residue 493 type sequence Q description BINDING SITE FOR RESIDUE MG C 12 source : AC2 3) chain C residue 401 type sequence W description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 4) chain C residue 409 type sequence L description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 5) chain C residue 430 type sequence F description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 6) chain C residue 460 type sequence T description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 7) chain C residue 461 type sequence G description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 8) chain C residue 462 type sequence S description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 9) chain C residue 463 type sequence G description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 10) chain C residue 464 type sequence K description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 11) chain C residue 465 type sequence T description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 12) chain C residue 466 type sequence S description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 13) chain C residue 493 type sequence Q description BINDING SITE FOR RESIDUE ATP C 3 source : AC7 14) chain C residue 541 type sequence L description BINDING SITE FOR RESIDUE ACY C 7 source : BC2 15) chain C residue 542 type sequence G description BINDING SITE FOR RESIDUE ACY C 7 source : BC2 16) chain C residue 545 type sequence G description BINDING SITE FOR RESIDUE ACY C 7 source : BC2 17) chain C residue 546 type sequence V description BINDING SITE FOR RESIDUE ACY C 7 source : BC2 18) chain C residue 547 type sequence T description BINDING SITE FOR RESIDUE ACY C 7 source : BC2 19) chain C residue 532 type sequence K description BINDING SITE FOR RESIDUE ACY D 9 source : BC4 20) chain C residue 552 type sequence Q description BINDING SITE FOR RESIDUE ACY D 9 source : BC4 21) chain C residue 524 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI6 22) chain C residue 670 type MOD_RES sequence S description Phosphoserine; by PKA => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI5 23) chain C residue 401 type BINDING sequence W description BINDING => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI1 24) chain C residue 493 type BINDING sequence Q description BINDING => ECO:0007744|PDB:1Q3H, ECO:0007744|PDB:1R0X, ECO:0007744|PDB:1R0Z, ECO:0007744|PDB:1XFA source Swiss-Prot : SWS_FT_FI3 25) chain C residue 458 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434, ECO:0007744|PDB:1Q3H, ECO:0007744|PDB:1R0X, ECO:0007744|PDB:1R0Z, ECO:0007744|PDB:1R10, ECO:0007744|PDB:1XF9, ECO:0007744|PDB:1XFA, ECO:0007744|PDB:3SI7 source Swiss-Prot : SWS_FT_FI2 26) chain C residue 549 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI4 27) chain C residue 660 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI4

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