eF-site ID 1r0x-B PDB Code 1r0x Chain B click to enlarge Title Cystic fibrosis transmembrane conductance regulator (CFTR) nucleotide-binding domain one (NBD1) with ATP Classification TRANSPORT PROTEIN Compound Cystic fibrosis transmembrane conductance regulator Source (CFTR_MOUSE) Sequence B:  TTGIIMENVTAFWEEGFGELLEKSFSHLCLVGNPVLKNIN LNIEKGEMLAITGSTGSGKTSLLMLILGELEASEGIIKHS GRVSFCSQFSWIMPGTIKENIIFGVSYDEYRYKSVVKACQ LQQDITKFAEQDNTVLGEGGVTLSGGQRARISLARAVYKD ADLYLLDSPFGYLDVFTEEQVFESCVCKLMANKTRILVTS KMEHLRKADKILILHQGSSYFYGTFSELQSLRPDFSSKLM GYDTFDQFTEERRSSILTETLRRFS Description Functional site 1) chain B residue 465 type sequence T description BINDING SITE FOR RESIDUE MG B 11 source : AC1 2) chain B residue 493 type sequence Q description BINDING SITE FOR RESIDUE MG B 11 source : AC1 3) chain B residue 498 type sequence M description BINDING SITE FOR RESIDUE ATP A 1 source : AC5 4) chain B residue 401 type sequence W description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 5) chain B residue 410 type sequence E description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 6) chain B residue 430 type sequence F description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 7) chain B residue 460 type sequence T description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 8) chain B residue 461 type sequence G description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 9) chain B residue 462 type sequence S description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 10) chain B residue 463 type sequence G description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 11) chain B residue 464 type sequence K description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 12) chain B residue 465 type sequence T description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 13) chain B residue 466 type sequence S description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 14) chain B residue 493 type sequence Q description BINDING SITE FOR RESIDUE ATP B 2 source : AC6 15) chain B residue 578 type sequence L description BINDING SITE FOR RESIDUE ACY A 5 source : AC9 16) chain B residue 542 type sequence G description BINDING SITE FOR RESIDUE ACY B 6 source : BC1 17) chain B residue 545 type sequence G description BINDING SITE FOR RESIDUE ACY B 6 source : BC1 18) chain B residue 546 type sequence V description BINDING SITE FOR RESIDUE ACY B 6 source : BC1 19) chain B residue 547 type sequence T description BINDING SITE FOR RESIDUE ACY B 6 source : BC1 20) chain B residue 532 type sequence K description BINDING SITE FOR RESIDUE ACY A 10 source : BC5 21) chain B residue 524 type LIPID sequence C description S-palmitoyl cysteine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI6 22) chain B residue 670 type MOD_RES sequence S description Phosphoserine; by PKA => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI5 23) chain B residue 401 type BINDING sequence W description BINDING => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI1 24) chain B residue 493 type BINDING sequence Q description BINDING => ECO:0007744|PDB:1Q3H, ECO:0007744|PDB:1R0X, ECO:0007744|PDB:1R0Z, ECO:0007744|PDB:1XFA source Swiss-Prot : SWS_FT_FI3 25) chain B residue 458 type BINDING sequence G description BINDING => ECO:0000255|PROSITE-ProRule:PRU00434, ECO:0007744|PDB:1Q3H, ECO:0007744|PDB:1R0X, ECO:0007744|PDB:1R0Z, ECO:0007744|PDB:1R10, ECO:0007744|PDB:1XF9, ECO:0007744|PDB:1XFA, ECO:0007744|PDB:3SI7 source Swiss-Prot : SWS_FT_FI2 26) chain B residue 549 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI4 27) chain B residue 660 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P13569 source Swiss-Prot : SWS_FT_FI4

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