eF-site ID 1r08-1234 PDB Code 1r08 Chain 1, 2, 3, 4 click to enlarge Title STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES Classification VIRUS Compound HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1) Source Human rhinovirus 14 (HRV-14) (POLG_HRV14) Sequence 1:  TVASISSGPKHTQKVPILTANETGATMPVLPSDSIETRTT YMHFNGSETDVECFLGRAACVHVTEIQNKDATGIDNHREA KLFNDWKINLSSLVQLRKKLELFTYVRFDSEYTILATASQ PDSANYSSNLVVQAMYVPPGAPNPKEWDDYTWQSASNPSV FFKVGDTSRFSVPYVGLASAYNCFYDGYSHDDAETQYGIT VLNHMGSMAFRIVNEHDEHKTLVKIRVYHRAKHVEAWIPR APRALPYTSIGRTNYPKNTEPVIKKRKGDIKSY 2:  GYSDRVQQITLGNSTITTQEAANAVVCYAEWPEYLPDVDA SDVNKTSKPDTSVCRFYTLDSKTWTTGSKGWCWKLPDALK DMGVFGQNMFFHSLGRSGYTVHVQCNATKFHSGCLLVVVI PEHQLASHEGGNVSVKYTFTHPGERGIDLSSANEVGGPVK DVLYNMNGTLLGNLLIFPHQFINLRTNNTATIVIPYINSV PIDSMTRHNNVSLMVIPIAPLTVPTGATPSLPITVTIAPM CTEFSGIRSKSIVPQ 3:  GLPTTTLPGSGQFLTTDDRQSPSALPNYEPTPRIHIPGKV HNLLEIIQVDTLIPMNNTHTKDEVNSYLIPLNANRQNEQV FGTNLFIGDGVFKTTLLGEIVQYYTHWSGSLRFSLMYTGP ALSSAKLILAYTPPGARGPQDRREAMLGTHVVWDIGLQST IVMTIPWTSGVQFRYTDPDTYTSAGFLSCWYQTSLILPPE TTGQVYLLSFISACPDFKLRLMKDTQTISQTVALTE 4:  INYYKDAASTSSAGQSLSMDPSKFTEPVKDLMLKGAPALN Description Functional site 1) chain 1 residue 104 type sequence I description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 2) chain 1 residue 106 type sequence L description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 3) chain 1 residue 107 type sequence S description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 4) chain 1 residue 116 type sequence L description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 5) chain 1 residue 128 type sequence Y description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 6) chain 1 residue 150 type sequence A description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 7) chain 1 residue 174 type sequence P description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 8) chain 1 residue 176 type sequence V description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 9) chain 1 residue 186 type sequence F description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 10) chain 1 residue 188 type sequence V description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 11) chain 1 residue 219 type sequence N description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 12) chain 1 residue 221 type sequence M description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 13) chain 1 residue 224 type sequence M description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 14) chain 3 residue 24 type sequence A description BINDING SITE FOR RESIDUE W42 1 900 source : AC1 15) chain 3 residue 25 type sequence L description BINDING SITE FOR RESIDUE W42 1 900 source : AC1

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